(E)-ethyl 3-((E)-1-allyl-7-bromo-2-oxoindolin-3-ylideneaminooxy)-2-(3-methoxybenzylidene)but-3-enoate | 1428942-54-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (E)-ethyl 3-((E)-1-allyl-7-bromo-2-oxoindolin-3-ylideneaminooxy)-2-(3-methoxybenzylidene)but-3-enoate
• 英文别名: ethyl (2E)-3-[(E)-(7-bromo-2-oxo-1-prop-2-enylindol-3-ylidene)amino]oxy-2-[(3-methoxyphenyl)methylidene]but-3-enoate
• CAS: 1428942-54-4
• 化学式: C₂₅H₂₃BrN₂O₅
• 分子量: 511.372
• InChiKey: HXFHKSIXLVNDNF-PTJVLCHRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  33
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  77.4
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  ethyl 2-(acetoxy(3-methoxyphenyl)methyl)buta-2,3-dienoate 、 (E)-1-allyl-7-bromo-3-(hydroxyimino)indolin-2-one 在 三乙烯二胺 作用下， 以 四氢呋喃 为溶剂， 反应 5.0h， 以90%的产率得到(E)-ethyl 3-((E)-1-allyl-7-bromo-2-oxoindolin-3-ylideneaminooxy)-2-(3-methoxybenzylidene)but-3-enoate
  参考文献：
  名称：

  Nitrogen-containing Lewis bases catalyzed highly regio- and stereoselective reactions of allenyl acetates with isatin-derived oximes

  摘要：

  Different nitrogen-containing Lewis bases catalyzed reactions of highly reactive allenyl acetates with isatin-derived oximes afforded the corresponding oxime ethers or nitrone derivatives in good to high yields with high regio- and stereoselectivities. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.02.070

文献信息

• Nitrogen-containing Lewis bases catalyzed highly regio- and stereoselective reactions of allenyl acetates with isatin-derived oximes
  作者：Yuan-Liang Yang、Yin Wei、Qin Xu、Min Shi

  DOI：10.1016/j.tet.2013.02.070

  日期：2013.4

  Different nitrogen-containing Lewis bases catalyzed reactions of highly reactive allenyl acetates with isatin-derived oximes afforded the corresponding oxime ethers or nitrone derivatives in good to high yields with high regio- and stereoselectivities. (C) 2013 Elsevier Ltd. All rights reserved.