3-(2-Bromethoxy)-octan | 61853-35-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-(2-Bromethoxy)-octan
• 英文别名: 3-(2-bromoethoxy)octane；3-(2-Bromoethoxy)octane
• CAS: 61853-35-8
• 化学式: C₁₀H₂₁BrO
• 分子量: 237.18
• InChiKey: CFWOCCWPZFDSTL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  12
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  辛烯 、 2-溴乙醇 在 [ClAuP(C6F5)3] 、 silver trifluoromethanesulfonate 、 三(五氟苯基)膦 作用下， 以 十三烷 、 甲苯 为溶剂， 反应 24.0h， 生成 2-(2-Bromethoxy)-octan 、 3-(2-Bromethoxy)-octan
  参考文献：
  名称：

  Enhancement of Reaction Efficiency by Functionalized Alcohols on Gold(I)-Catalyzed Intermolecular Hydroalkoxylation of Unactivated Olefins

  摘要：

  Intermolecular hydroalkoxylation of unactivated olefins catalyzed by the combination of gold(I) and electron deficient phosphine ligands has been developed. Although pairings of unactivated olefins and common aliphatic alcohols gave unsatisfactory results In gold catalyzed hydroalkoxylations, the use of alcohol substrates bearing coordination functionalities such as halogen or alkoxy groups showed great improvement of reactivity.

  DOI：

  10.1021/ol9023166

文献信息

• Enhancement of Reaction Efficiency by Functionalized Alcohols on Gold(I)-Catalyzed Intermolecular Hydroalkoxylation of Unactivated Olefins
  作者：Toshifumi Hirai、Akiyuki Hamasaki、Aki Nakamura、Makoto Tokunaga

  DOI：10.1021/ol9023166

  日期：2009.12.3

  Intermolecular hydroalkoxylation of unactivated olefins catalyzed by the combination of gold(I) and electron deficient phosphine ligands has been developed. Although pairings of unactivated olefins and common aliphatic alcohols gave unsatisfactory results In gold catalyzed hydroalkoxylations, the use of alcohol substrates bearing coordination functionalities such as halogen or alkoxy groups showed great improvement of reactivity.