trifluoro(quinolin-1-ium-1-yl)boranuide | 772-93-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: trifluoro(quinolin-1-ium-1-yl)boranuide
• CAS: 772-93-0
• 化学式: C₉H₇BF₃N
• 分子量: 196.967
• InChiKey: XMXDAYAFZVMJTD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  lithium di-tert-butyltetramethylpiperidinozincate 、 trifluoro(quinolin-1-ium-1-yl)boranuide 在 水 作用下， 以 四氢呋喃 为溶剂， 反应 3.5h， 以35%的产率得到2-叔丁基喹啉
  参考文献：
  名称：

  Trimethyl borate-induced one-pot homologation reactions of isoquinoline with di-tert-butyl-TMP zincate

  摘要：

  Novel one-pot homologation reactions of isoquinoline and quinoline with di-tert-butyl-TMP zincate/trimethyl borate are described. 1-tert-Butyl-3,4-dihydroisoquinoline 1 and 1-tert-butylisoquinoline 2 are formed unexpectedly under the presented reaction conditions with relative ease. A reaction mechanism, including 1,2-migration of the tert-butyl group from 1-isoquinolylzincate, is proposed in detail. Migratory aptitudes of other ligands of isoquinolyl zincates are also discussed. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.05.045
• 作为产物：
  描述：

  喹啉 、 三氟化硼乙醚 反应 2.0h， 生成 trifluoro(quinolin-1-ium-1-yl)boranuide
  参考文献：
  名称：

  Trimethyl borate-induced one-pot homologation reactions of isoquinoline with di-tert-butyl-TMP zincate

  摘要：

  Novel one-pot homologation reactions of isoquinoline and quinoline with di-tert-butyl-TMP zincate/trimethyl borate are described. 1-tert-Butyl-3,4-dihydroisoquinoline 1 and 1-tert-butylisoquinoline 2 are formed unexpectedly under the presented reaction conditions with relative ease. A reaction mechanism, including 1,2-migration of the tert-butyl group from 1-isoquinolylzincate, is proposed in detail. Migratory aptitudes of other ligands of isoquinolyl zincates are also discussed. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.05.045