| 1036637-22-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1036637-22-5
• 化学式: C₂₆H₄₄N₄O₉
• 分子量: 556.657
• InChiKey: NRRPMAUBTBJRAI-ZFXZZAOISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.87
• 重原子数：
  39.0
• 可旋转键数：
  19.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  175.22
• 氢给体数：
  1.0
• 氢受体数：
  10.0

反应信息

• 作为反应物：
  描述：

  在 sodium methylate 作用下， 以 甲醇 为溶剂， 反应 1.0h， 以97%的产率得到12-azidododecyl 2-acetamido-2-deoxy-β-D-glucopyranoside
  参考文献：
  名称：

  Chemical and enzymatic synthesis of neoglycolipids in the presence of cyclodextrins

  摘要：

  The efficiency of cyclodextrins (CDs), alpha-CD, beta-CD and gamma-CD, for the blotting of hydrophobic substrates to water-soluble polymers and for the synthesis of neoglycolipids using glycosyltransferase is described. CDs did not disturb HPLC purification and did not bring lather. These merits are superior to surfactants commonly used in such a case. The utility of CDs as a novel and efficient supporting material for enzymatic glycosylation is also discussed. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.03.103
• 作为产物：
  描述：

  、 乙酸酐 在 吡啶 作用下， 反应 5.0h， 生成
  参考文献：
  名称：

  Chemical and enzymatic synthesis of neoglycolipids in the presence of cyclodextrins

  摘要：

  The efficiency of cyclodextrins (CDs), alpha-CD, beta-CD and gamma-CD, for the blotting of hydrophobic substrates to water-soluble polymers and for the synthesis of neoglycolipids using glycosyltransferase is described. CDs did not disturb HPLC purification and did not bring lather. These merits are superior to surfactants commonly used in such a case. The utility of CDs as a novel and efficient supporting material for enzymatic glycosylation is also discussed. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.03.103