2-Acyl-3,4-dimethylthiazolium triflates, modelled upon the biologically important 2-acyl thiamine derivatives, react in neutral media specifically with the oxygen atom of N-aryl hydroxylami'nes to give rise to tetrahedral intermediates, which collapse to the O-acyl derivatives under mildly basic conditions.
2-酰基-3,4-二甲基
噻唑鎓
三氟甲磺酸盐以具有重要
生物学意义的2-酰基
硫胺素衍
生物为模型,在中性介质中与N-芳基
羟胺的氧原子发生反应,生成四面体中间体,在弱碱性条件下,该中间体会分解为O-酰基衍
生物。