2-C-(hydroxymethyl)-5-deoxy-L-ribose | 1175531-29-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-C-(hydroxymethyl)-5-deoxy-L-ribose
• 英文别名: (2S,3S,4S)-2,3,4-trihydroxy-2-(hydroxymethyl)pentanal
• CAS: 1175531-29-9
• 化学式: C₆H₁₂O₅
• 分子量: 164.158
• InChiKey: SLWMPTXQUJSLKT-ZLUOBGJFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.6
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  98
• 氢给体数：
  4
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  L-rhamnulose 在 molybdic acid 作用下， 以 water-d2 为溶剂， 反应 0.08h， 生成 2-C-(hydroxymethyl)-5-deoxy-L-ribose
  参考文献：
  名称：

  The influence of microwave irradiation on stereospecific Mo(VI)-catalyzed transformation of deoxysugars

  摘要：

  The stereospecific mutual isomerization of 5-, 6-, and 7-deoxysugars in a microwave field with Mo(VI) as a catalyst is reported. The reaction cycle allows the use of catalytic amounts of molybdate ions to form highly reactive catalytically active dimolybdate complexes that create conditions for stereospecific intramolecular rearrangement. The microwave-enhanced Mo(VI)-catalyzed transformation of deoxyaldoses occurred with full stereospecificity resulting in the formation of the corresponding epi-deoxyaldoses in very good yields. The microwave field has a Substantial effect on the transformation studied. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2009.05.010