prop-2-ynyl-succinic acid-anhydride | 98550-42-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: prop-2-ynyl-succinic acid-anhydride
• 英文别名: Prop-2-inyl-bernsteinsaeure-anhydrid；3-(Prop-2-yn-1-yl)oxolane-2,5-dione；3-prop-2-ynyloxolane-2,5-dione
• CAS: 98550-42-6
• 化学式: C₇H₆O₃
• mdl: MFCD18432058
• 分子量: 138.123
• InChiKey: QLTWDRPUZFBSDC-UHFFFAOYSA-N

物化性质

• 沸点：
  168-171 °C(Press: 28 Torr)
• 密度：
  1.248±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.428
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  马来酸酐 、 丙二烯 在 对苯二酚 、 苯 作用下， 生成 prop-2-ynyl-succinic acid-anhydride 、 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Stevenson et al., Organic syntheses. Collective volume, 1973, vol. V, p. 459,460

  摘要：

  DOI：

文献信息

• TRANSLOCATION OF A POLYMER THROUGH A NANOPORE
  申请人：ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY

  公开号：US20160018384A1

  公开（公告）日：2016-01-21

  Embodiments of the present disclosure are directed to methods, systems and devices, for analyzing the molecules. For example, in some embodiments, a system is provided which includes a first volume of conducting fluid, a second volume of conducting fluid, an orifice in communication with said first and second volumes of fluid, and means for applying an electric potential difference between said first and second volumes of fluid. In some such embodiments, a conjugate product is provided which comprises charged polymers each having attached thereto at least one first molecule for analysis, where the product carries a predetermined charge greater than the charge on the first molecule, and upon dissolving a product in the first volume of fluid, the product is directed into the orifice.

  本公开的实施例涉及分析分子的方法、系统和装置。例如，在某些实施例中，提供了一种系统，该系统包括第一容积的导电液体、第二容积的导电液体、与所述第一和第二容积的液体通信的孔口，以及用于在所述第一和第二容积的液体之间施加电势差的手段。在某些这样的实施例中，提供了一种共轭产物，其中包括带电聚合物，每个聚合物上至少连接有一种用于分析的第一分子，该产物携带预定电荷，大于第一分子的电荷，在将产物溶解于第一容积的液体中时，将产物引导进入孔口。
• Translocation of a polymer through a nanopore
  申请人：Arizona Board of Regents on behalf of Arizona State University

  公开号：US10267785B2

  公开（公告）日：2019-04-23

  Embodiments of the present disclosure are directed to methods, systems and devices, for analyzing the molecules. For example, in some embodiments, a system is provided which includes a first volume of conducting fluid, a second volume of conducting fluid, an orifice in communication with the first and second volumes of fluid, and means for applying an electric potential difference between the first and second volumes of fluid. In some such embodiments, a conjugate product is provided which includes charged polymers each having attached thereto at least one first molecule for analysis, where the product carries a predetermined charge greater than the charge on the first molecule, and upon dissolving the product in the first volume of fluid, the product is directed into the orifice.

  本公开的实施方案涉及用于分析分子的方法、系统和设备。例如，在某些实施例中，提供了一种系统，该系统包括第一体积导电流体、第二体积导电流体、与第一和第二体积流体相通的孔口，以及在第一和第二体积流体之间施加电势差的装置。在一些这样的实施方案中，提供了一种共轭产品，其中包括带电聚合物，每个聚合物上都附有至少一个用于分析的第一分子，产品所带的预定电荷大于第一分子上的电荷，将产品溶解在第一体积流体中后，产品被导入孔口。
• Chemistry of Cyclobutanes. I. Synthesis of Methylenecyclobutanes
  作者：H. N. Cripps、J. K. Williams、W. H. Sharkey

  DOI：10.1021/ja01520a033

  日期：1959.6
• Alder; Ackermann, Chemische Berichte, 1954, vol. 87, p. 1567
  作者：Alder、Ackermann

  DOI：——

  日期：——
• Thermal Dimerization of Allene to 1,2-Dimethylenecyclobutane¹
  作者：A. T. Blomquist、Joseph A. Verdol

  DOI：10.1021/ja01582a033

  日期：1956.1