(3aR,5R,6S,6aR)-5-(1-benzyl-4,5-diphenylimidazol-2-yl)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol | 1013925-50-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: (3aR,5R,6S,6aR)-5-(1-benzyl-4,5-diphenylimidazol-2-yl)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol
• CAS: 1013925-50-2
• 化学式: C₂₉H₂₈N₂O₄
• 分子量: 468.552
• InChiKey: BPWXITPHIBKLCZ-WDTRASESSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  35
• 可旋转键数：
  5
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  65.7
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  联苯甲酰 、 苄胺 、 1,2-O-异亚丙基-alpha-D-木糖基-戊二醛-1,4-呋喃糖 在 K5 ammonium acetate 作用下， 反应 2.0h， 以60.8%的产率得到(3aR,5R,6S,6aR)-5-(1-benzyl-4,5-diphenylimidazol-2-yl)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol
  参考文献：
  名称：

  Synthesis and antimicrobial activity of novel C-linked imidazole glycoconjugates

  摘要：

  Novel C-linked imidazole derivatives have been synthesized in good to excellent yields and characterized by analytical and spectral analysis. Four of the newly synthesized compounds exhibited moderate antibacterial activity. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2007.11.118

文献信息

• Synthesis and antimicrobial activity of novel C-linked imidazole glycoconjugates
  作者：Lingaiah Nagarapu、A. Satyender、B. Rajashaker、K. Srinivas、P. Rupa rani、K. Radhika、G. Subhashini

  DOI：10.1016/j.bmcl.2007.11.118

  日期：2008.2

  Novel C-linked imidazole derivatives have been synthesized in good to excellent yields and characterized by analytical and spectral analysis. Four of the newly synthesized compounds exhibited moderate antibacterial activity. (C) 2007 Elsevier Ltd. All rights reserved.