| 1416474-10-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1416474-10-6
• 化学式: C₁₉H₁₈F₂O₂
• 分子量: 316.348
• InChiKey: HDUJVWYCXDLVRA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.98
• 重原子数：
  23.0
• 可旋转键数：
  8.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  34.14
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  在 sodium methylate 、 potassium iodide 作用下， 以 甲醇 为溶剂， 以67%的产率得到cyclopentane-1,2-diylbis[(4-fluorophenyl)methanone]
  参考文献：
  名称：

  Anodic Cyclization of 1,7-Diarylheptane-1,7-diones to the Corresponding 1,2-Diaroylcyclopentanes

  摘要：

  A range of 1,7-diarylheptane-1,7-diones were electro-oxidized in the presence of iodide ions and a base in a mixture of methanol and toluene as the reaction solvents to give the corresponding cyclized 1,2-diaroylcyclopentanes in moderate to good yields. The reactions were carried out under extremely mild reaction conditions for which the optimal amount of electrolytic current varied from 2.05-3.17 F.mol(-1) depending on the substrates. The reaction presumably proceeds through a two-electron oxidation process in which the iodide ion plays an important role as the electron carrier.

  DOI：

  10.1055/s-0032-1317206
• 作为产物：
  描述：

  氟苯 、 1,7-庚二酰氯 在 aluminum (III) chloride 作用下， 生成
  参考文献：
  名称：

  Anodic Cyclization of 1,7-Diarylheptane-1,7-diones to the Corresponding 1,2-Diaroylcyclopentanes

  摘要：

  A range of 1,7-diarylheptane-1,7-diones were electro-oxidized in the presence of iodide ions and a base in a mixture of methanol and toluene as the reaction solvents to give the corresponding cyclized 1,2-diaroylcyclopentanes in moderate to good yields. The reactions were carried out under extremely mild reaction conditions for which the optimal amount of electrolytic current varied from 2.05-3.17 F.mol(-1) depending on the substrates. The reaction presumably proceeds through a two-electron oxidation process in which the iodide ion plays an important role as the electron carrier.

  DOI：

  10.1055/s-0032-1317206