2-methyl-quinolin-3-ol-1-oxide | 103264-08-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-methyl-quinolin-3-ol-1-oxide
• 英文别名: 2-Methyl-chinolin-3-ol-1-oxid
• CAS: 103264-08-0
• 化学式: C₁₀H₉NO₂
• 分子量: 175.187
• InChiKey: OXRQHZVAACSFLH-UHFFFAOYSA-N

物化性质

• 沸点：
  381.5±34.0 °C(Predicted)
• 密度：
  1.24±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.49
• 重原子数：
  13.0
• 可旋转键数：
  0.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  47.17
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  2-甲基喹啉 在 水 、 双氧水 、 溶剂黄146 作用下， 生成 2-甲基喹啉N-氧化物 、 2-methyl-quinolin-3-ol-1-oxide
  参考文献：
  名称：

  Complications of Unsafe Abortion: A Case Study and the Need for Abortion Law Reform in Nigeria

  摘要：

  Complications of unsafe abortion account for 30-40% of maternal deaths in Nigeria. This paper reports a case of unsafe abortion by dilatation and curettage, carried out by a medical practitioner in a private clinic on a 20-year-old single girl in Lagos, Nigeria. The girl was 16 weeks pregnant. She suffered complications consisting of perforation of the vaginal wall through the utero-vesical space into the abdominal cavity with gangrenous loops of small intestine herniating through it. Information was obtained from her case notes and the operating theatre register. She had a resection and anastomosis of the small intestine and had to remain in hospital, where she made a full recovery, for two weeks. Unsafe abortion is fraught with many complications, including pelvic sepsis, septicaemia, haemorrhage, renal failure, uterine perforation and other genital tract injuries, and gastro-intestinal tract injuries. Where expert, emergency treatment for these is not available, women die. Unsafe abortion procedures, untrained abortion service providers, restrictive laws and high morbidity and mortality from abortion tend to occur together. We advocate for a review of the existing restrictive laws in Nigeria in order to reduce the high morbidity and mortality from unsafe abortion. (C) 2002 Reproductive Health Matters. Published by Elsevier Science. All rights reserved.

  DOI：

  10.1016/s0968-8080(02)00024-1