| 181026-05-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 181026-05-1
• 化学式: C₄₁H₆₂O₂₃
• 分子量: 922.929
• InChiKey: WWVGGTUALUHWLU-BHUUIQCZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.64
• 重原子数：
  64.0
• 可旋转键数：
  19.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  270.33
• 氢给体数：
  1.0
• 氢受体数：
  23.0

反应信息

• 作为反应物：
  描述：

  在 2,6-二叔丁基-4-甲基吡啶 、 4 A molecular sieve 、 氢气 、 silver trifluoromethanesulfonate 作用下， 以 乙醇 、 二氯甲烷 、 溶剂黄146 为溶剂， 生成
  参考文献：
  名称：

  Chemical approaches to bacterial vaccines. synthesis of mycobacterial oligosaccharide-protein conjugates for use as serodiagnostics and immunogens

  摘要：

  Di- to penta-saccharide fragments (2-5) of Polysaccharide II (PS-II) of Mycobacterium tuberculosis were synthesized in spacer-linked form in a stepwise fashion using a new glycosyl donor featuring a trans-fused isopropylidene diol-protecting group. Covalent attachment of the oligosaccharides to proteins provides semi-synthetic antigens and immunogens which are being used to probe the role of PS-II as a possible mycobacterial antigen.

  DOI：

  10.1016/0960-894x(96)00235-1
• 作为产物：
  描述：

  在 氢气 作用下， 生成
  参考文献：
  名称：

  Chemical approaches to bacterial vaccines. synthesis of mycobacterial oligosaccharide-protein conjugates for use as serodiagnostics and immunogens

  摘要：

  Di- to penta-saccharide fragments (2-5) of Polysaccharide II (PS-II) of Mycobacterium tuberculosis were synthesized in spacer-linked form in a stepwise fashion using a new glycosyl donor featuring a trans-fused isopropylidene diol-protecting group. Covalent attachment of the oligosaccharides to proteins provides semi-synthetic antigens and immunogens which are being used to probe the role of PS-II as a possible mycobacterial antigen.

  DOI：

  10.1016/0960-894x(96)00235-1