2-Propenoic acid, 3-(3H-imidazo[4,5-b]pyridin-6-yl)-, (2E)- | 335030-65-4

• 物质功能分类: 有机原料 - 杂环化合物
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并吡啶类
• 英文名称: 2-Propenoic acid, 3-(3H-imidazo[4,5-b]pyridin-6-yl)-, (2E)-
• 英文别名: 3-(1H-imidazo[4,5-b]pyridin-6-yl)prop-2-enoic acid
• CAS: 335030-65-4
• 化学式: C₉H₇N₃O₂
• 分子量: 189.17
• InChiKey: JMDBUAOMYBSWKN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  78.9
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• FAB I inhibitors
  申请人：Miller H. William

  公开号：US20050250810A1

  公开（公告）日：2005-11-10

  Compounds of the formula (I) are disclosed which are Fab I inhibitors and are useful in the treatment of bacterial infections.

  公式（I）的化合物被揭示为Fab I抑制剂，可用于治疗细菌感染。
• Fab I inhibitors
  申请人：Burgess J. Walter

  公开号：US20060116394A1

  公开（公告）日：2006-06-01

  Compounds are disclosed which are Fab I inhibitors and are useful in the treatment bacterial infections.

  本发明揭示了一种Fab I抑制剂，可用于治疗细菌感染。
• Compositions comprising multiple bioactive agents, and methods of using the same
  申请人：Berman M. Judd

  公开号：US20060142265A1

  公开（公告）日：2006-06-29

  In part, the present invention is directed to compositions comprising a FabI inhibitor and at least one other bioactive agent. In another part, the present invention is directed to antibacterial compositions comprising a compound of formulas I-III and at least one other antibacterial agent.

  本发明的一部分涉及含有FabI抑制剂和至少一种其他生物活性剂的组合物。另一部分，本发明涉及含有I-III式化合物和至少一种其他抗菌剂的抗菌组合物。
• Fab I Inhibitors
  申请人：Burgess Walter J.

  公开号：US20090221699A1

  公开（公告）日：2009-09-03

  Compounds are disclosed which are Fab I inhibitors and are useful in the treatment bacterial infections.

  本发明揭示了一种Fab I抑制剂，可用于治疗细菌感染。
• Compositions Comprising Multiple Bioactive Agents, and Methods of Using the Same
  申请人：BERMAN JUDD M.

  公开号：US20120010127A1

  公开（公告）日：2012-01-12

  In part, the present invention is directed to compositions comprising a FabI inhibitor and at least one other bioactive agent. In another part, the present invention is directed to antibacterial compositions comprising a compound of formulas I-III and at least one other antibacterial agent.

  本发明的一部分涉及包含FabI抑制剂和至少一种其他生物活性剂的组合物。另一部分涉及包含I-III式化合物和至少一种其他抗菌剂的抗菌组合物。