1-isonicotinoyl-5-(4-methoxycarbonylphenyl)dipyrromethane | 1452517-88-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-isonicotinoyl-5-(4-methoxycarbonylphenyl)dipyrromethane
• CAS: 1452517-88-2
• 化学式: C₂₃H₁₉N₃O₃
• 分子量: 385.422
• InChiKey: KANKBOWOFIKJIW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.94
• 重原子数：
  29.0
• 可旋转键数：
  6.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  87.84
• 氢给体数：
  2.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  1-isonicotinoyl-5-(4-methoxycarbonylphenyl)dipyrromethane 在 1,8-二氮杂双环[5.4.0]十一碳-7-烯 、 ytterbium(III) triflate 作用下， 以 甲苯 、 乙腈 为溶剂， 反应 2.0h， 生成 5-(4-methoxycarbonylphenyl)-10,15,20-tris(4-pyridyl)porphyrinatomagnesium
  参考文献：
  名称：

  Two-Photon Oxygen Sensing with Quantum Dot-Porphyrin Conjugates

  摘要：

  Supramolecular assemblies of a quantum dot (QD) associated to palladium(II) porphyrins have been developed to detect oxygen (pO(2)) in organic solvents. Palladium porphyrins are sensitive in the 0-160 Torr range, making them ideal phosphors for in vivo biological oxygen quantification. Porphyrins with meso pyridyl substituents bind to the surface of the QD to produce self-assembled nanosensors. Appreciable overlap between QD emission and porphyrin absorption features results in efficient Forster resonance energy transfer (FRET) for signal transduction in these sensors. The QD serves as a photon antenna, enhancing porphyrin emission under both one- and two-photon excitation, demonstrating that QD-palladium porphyrin conjugates may be used for oxygen sensing over physiological oxygen ranges.

  DOI：

  10.1021/ic4011168
• 作为产物：
  描述：

  氯化异氰盐酸盐 在 乙基溴化镁 作用下， 以 四氢呋喃 为溶剂， 反应 6.5h， 生成 1-isonicotinoyl-5-(4-methoxycarbonylphenyl)dipyrromethane
  参考文献：
  名称：

  Two-Photon Oxygen Sensing with Quantum Dot-Porphyrin Conjugates

  摘要：

  Supramolecular assemblies of a quantum dot (QD) associated to palladium(II) porphyrins have been developed to detect oxygen (pO(2)) in organic solvents. Palladium porphyrins are sensitive in the 0-160 Torr range, making them ideal phosphors for in vivo biological oxygen quantification. Porphyrins with meso pyridyl substituents bind to the surface of the QD to produce self-assembled nanosensors. Appreciable overlap between QD emission and porphyrin absorption features results in efficient Forster resonance energy transfer (FRET) for signal transduction in these sensors. The QD serves as a photon antenna, enhancing porphyrin emission under both one- and two-photon excitation, demonstrating that QD-palladium porphyrin conjugates may be used for oxygen sensing over physiological oxygen ranges.

  DOI：

  10.1021/ic4011168