5-carboxypentyl 2,4-di-O-acetyl-3,6-di-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-mannopyranoside | 1151931-89-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-carboxypentyl 2,4-di-O-acetyl-3,6-di-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-mannopyranoside
• CAS: 1151931-89-3
• 化学式: C₄₄H₆₂O₂₈
• 分子量: 1038.96
• InChiKey: JCNAEOGVHWLLCP-SPOTWWOLSA-N

物化性质

• 沸点：
  918.0±65.0 °C(predicted)
• 密度：
  1.38±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

反应信息

• 作为反应物：
  描述：

  N-羟基丁二酰亚胺 、 5-carboxypentyl 2,4-di-O-acetyl-3,6-di-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-mannopyranoside 在 N,N'-二环己基碳二亚胺 作用下， 以 乙酸乙酯 为溶剂， 反应 16.0h， 以218 mg的产率得到5-(N-succinimidyloxycarbonyl)pentyl 2,4-di-O-acetyl-3,6-di-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-mannopyranoside
  参考文献：
  名称：

  The synthesis and immune stimulating action of mannose-capped lysine-based dendrimers

  摘要：

  The syntheses of monodisperse lysine dendrimers, capped with two to sixty-four mono-, di- and tri-alpha-D-mannopyranosyl residues are described. These syntheses used reactive N-hydroxysuccinimide esters to ensure complete reaction of dendrimer amines with the mannosylating reagents. The purities of the dendrimers were established by RP-HPLC and MALDI-TOF mass spectrometry and were found to be excellent. The relative ability of these glycodendrimers to induce dendritic cell Maturation was measured, however, no significant trends were observed. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.02.018
• 作为产物：
  描述：

  乙酸酐 、 5-carboxypentyl (α-D-mannopyranosyl)-(1->3)-[(α-D-mannopyranosyl)-(1->6)]-α-D-mannopyranoside 在 吡啶 作用下， 反应 16.0h， 生成 5-carboxypentyl 2,4-di-O-acetyl-3,6-di-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-mannopyranoside
  参考文献：
  名称：

  The synthesis and immune stimulating action of mannose-capped lysine-based dendrimers

  摘要：

  The syntheses of monodisperse lysine dendrimers, capped with two to sixty-four mono-, di- and tri-alpha-D-mannopyranosyl residues are described. These syntheses used reactive N-hydroxysuccinimide esters to ensure complete reaction of dendrimer amines with the mannosylating reagents. The purities of the dendrimers were established by RP-HPLC and MALDI-TOF mass spectrometry and were found to be excellent. The relative ability of these glycodendrimers to induce dendritic cell Maturation was measured, however, no significant trends were observed. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.02.018