2,3-bis(1-methylethoxy)-6-methoxycyclopenta[b]quinolin-1-ol | 1038779-42-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2,3-bis(1-methylethoxy)-6-methoxycyclopenta[b]quinolin-1-ol
• CAS: 1038779-42-8
• 化学式: C₁₉H₂₃NO₄
• 分子量: 329.396
• InChiKey: TWHZUPNKWKHOBL-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  2,3-bis(1-methylethoxy)-6-methoxycyclopenta[b]quinolin-1-one 在 sodium tetrahydroborate 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 以70%的产率得到2,3-bis(1-methylethoxy)-6-methoxycyclopenta[b]quinolin-1-ol
  参考文献：
  名称：

  A novel entry to cyclopenta[b]quinolines via thermal ring-expansion of (2-aminophenyl)-ethynyl-substituted squaric acid derivatives

  摘要：

  Substituted cyclopenta[b]quinolin-1-ones were prepared by thermal ring-expansion of substituted N-Boc protected 4-(2-aminophenylethynyl)-4-hydroxy-2-cyclobuten-1-ones forming the corresponding 2-aminophenylmethylidene substituted 4-cyclopentene-1,3-diones. Deprotection of the amine resulted in spontaneous condensation giving cyclopenta[b]quinolin-1-ones. Sodium borohydride reduction of these products produced cyclopenta[b]quinolin-1-ols. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.03.025