1-[3-(3,4-dimethoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]ethanone;oxovanadium(2+);sulfate | 180298-01-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 1-[3-(3,4-dimethoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]ethanone;oxovanadium(2+);sulfate
• CAS: 180298-01-5
• 化学式: C₃₄H₃₆N₄O₁₁S₃V
• 分子量: 823.82
• InChiKey: XJKQNUKIGPMVSX-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  oxovanadium(IV) sulfate 、 1-acetyl-5-(3,4-dimethoxyphenyl)-3-(thienyl)-2-pyrazoline 以 乙醇 、 水 为溶剂， 以68%的产率得到1-[3-(3,4-dimethoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]ethanone;oxovanadium(2+);sulfate
  参考文献：
  名称：

  Ligational Behaviour of Substituted 4,5-Dihydropyrazoles Towards Oxovanadium(IV) and Metalation Effect on the Antimicrobial Activity

  摘要：

  Complexes of 1-acetyl-5-aryl-3-(substituted thienyl)-4,5-dihydropyrazoles [AATP; Ar = 2-OCH3, 4-OCH3 and 3,4-(OCH3)(2)] with oxovanadium(IV) ion have been synthesized and characterized on the basis of elemental analyses, molar conductance, magnetic susceptibility, molecular weight determination and spectral (ESR, IR and UV) data. The pyrazoles behaved as bidentate ligands coordinating through oxygen and nitrogen N(2) of the carbonyl and azomethine groups, respectively. ESR data of the powdered samples of the complexes and in DMF solution suggested a distorted octahedral environment around oxovanadium(IV). The ligands and vanadyl complexes were evaluated for antifungal activity against Colletotrichum capsicum and Rhizoctonia solani at 37 degrees C and antibacterial activity against Bacillus subtilis and Escherichia coli at 28 degrees C. Metalation had pronounced effects on the antimicrobial activity of the ligands.

  DOI：

  10.1080/00945719608004344