61,63-Di-O-trityl-cG7 permethylate | 139622-72-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 61,63-Di-O-trityl-cG7 permethylate
• 英文别名: 6¹,6³-Di-O-trityl-cG₇ permethylate
• CAS: 139622-72-3
• 化学式: C₉₉H₁₃₆O₃₅
• 分子量: 1886.15
• InChiKey: NCJICKCMAQHLPE-RXMSSMPFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.23
• 重原子数：
  134.0
• 可旋转键数：
  36.0
• 环数：
  27.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  323.05
• 氢给体数：
  0.0
• 氢受体数：
  35.0

反应信息

• 作为反应物：
  描述：

  61,63-Di-O-trityl-cG7 permethylate 在 溶剂黄146 作用下， 反应 1.0h， 生成 heptakis(2,3-di-O-methyl)-6^B,6^D,6^E,6^F,6^G-penta-O-methyl-β-cyclodextrin
  参考文献：
  名称：

  Preparation of di-O-triphenylmethyl-(trityl)-cyclomalto-hexaoses and -cyclomaltoheptaoses and characterization of three positional isomers of each by the “hex-5-enose degradation”

  摘要：

  Regioisomeric 6l,6n-di-O-trityl-cyclomaltohexaoses (cG6s) or -cyclomaltoheptaoses (cG7s) were prepared by the reaction of cyclomaltohexaose (1, cG6) or cylomaltoheptaose (5, cG7) with chlorotriphenylmethane methane in pyridine and isolation by h.p.l.c. The regiochemical determination of each three ditrityl-substituted substituted derivatives has been accomplished by the "hex-5-enose degradation", followed by measurement of their f.a.b.-mass spectra.

  DOI：

  10.1016/0008-6215(92)80001-h
• 作为产物：
  描述：

  61,63-Di-O-tritylcyclomaltoheptaose 、 碘甲烷 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 5.0h， 以61.2%的产率得到61,63-Di-O-trityl-cG7 permethylate
  参考文献：
  名称：

  Preparation of di-O-triphenylmethyl-(trityl)-cyclomalto-hexaoses and -cyclomaltoheptaoses and characterization of three positional isomers of each by the “hex-5-enose degradation”

  摘要：

  Regioisomeric 6l,6n-di-O-trityl-cyclomaltohexaoses (cG6s) or -cyclomaltoheptaoses (cG7s) were prepared by the reaction of cyclomaltohexaose (1, cG6) or cylomaltoheptaose (5, cG7) with chlorotriphenylmethane methane in pyridine and isolation by h.p.l.c. The regiochemical determination of each three ditrityl-substituted substituted derivatives has been accomplished by the "hex-5-enose degradation", followed by measurement of their f.a.b.-mass spectra.

  DOI：

  10.1016/0008-6215(92)80001-h