methyl 1,3-isopropylidene-4-O-acetyl-6-deoxy-6-iodo-α-D-fructofuranoside | 1159494-95-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl 1,3-isopropylidene-4-O-acetyl-6-deoxy-6-iodo-α-D-fructofuranoside
• CAS: 1159494-95-7
• 化学式: C₁₂H₁₉IO₆
• 分子量: 386.184
• InChiKey: MSDAKKMHSHLNPS-SVDPJWKOSA-N

物化性质

• 沸点：
  382.9±42.0 °C(predicted)
• 密度：
  1.60±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

反应信息

• 作为反应物：
  描述：

  methyl 1,3-isopropylidene-4-O-acetyl-6-deoxy-6-iodo-α-D-fructofuranoside 、 三甲氧基磷 反应 60.0h， 以80%的产率得到methyl 1,3-isopropylidene-4-O-acetyl-6-deoxy-6-dimethoxyphosphinyl-α-D-fructofuranoside
  参考文献：
  名称：

  Facile synthesis of core intermediates toward sialyl nucleoside mimetics

  摘要：

  6-Deoxyphosphonated intermediates, 8 and 12, were efficiently synthesized from D-fructose and sucrose, respectively. These novel intermediates will be useful to synthesize various D-tagato- and fructofuranoside derivatives as inhibitors of sialyl transferase or sialidase. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.03.050
• 作为产物：
  描述：

  methyl 1,3-isopropylidene-4-O-acetyl-6-O-(p-tolylsulfonyl)-α-D-fructofuranoside 在 sodium iodide 作用下， 以 丙酮 为溶剂， 反应 5.0h， 以79%的产率得到methyl 1,3-isopropylidene-4-O-acetyl-6-deoxy-6-iodo-α-D-fructofuranoside
  参考文献：
  名称：

  Facile synthesis of core intermediates toward sialyl nucleoside mimetics

  摘要：

  6-Deoxyphosphonated intermediates, 8 and 12, were efficiently synthesized from D-fructose and sucrose, respectively. These novel intermediates will be useful to synthesize various D-tagato- and fructofuranoside derivatives as inhibitors of sialyl transferase or sialidase. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.03.050