methyl 5-acetamido-2-O-acetyl-3,5-dideoxy-8,9-O-isopropylidene-4-O-tert-butyldimethylsilyl-D-glycero-D-galacto-nonulopyranosonate | 121409-08-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl 5-acetamido-2-O-acetyl-3,5-dideoxy-8,9-O-isopropylidene-4-O-tert-butyldimethylsilyl-D-glycero-D-galacto-nonulopyranosonate
• CAS: 121409-08-3
• 化学式: C₂₃H₄₁NO₁₀Si
• 分子量: 519.665
• InChiKey: YPLKGSSWDYIBML-ADWCYLKFSA-N

反应信息

• 作为产物：
  描述：

  methyl 5-acetamido, 3,5-dideoxy-8,9-O-isopropylidene-Dglycero-β-D-galacto-2-nonulopyranosonate 在 吡啶 、 咪唑 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 4.0h， 生成 methyl 5-acetamido-2-O-acetyl-3,5-dideoxy-8,9-O-isopropylidene-4-O-tert-butyldimethylsilyl-D-glycero-D-galacto-nonulopyranosonate
  参考文献：
  名称：

  Synthesis of 7-O-acetyl-N-acetylneuraminic acid derivative.

  摘要：

  Selective protection of the C-4, C-8, and C-9 hydroxy groups of methyl (methyl 5-acetamido-3, 5-dideoxy-D-glycero-α-D-galacto-nonulopyranosid) onate followed by acetylation of the C-7 hy-droxy group gave a 7-O-acetyl-N-acetylneuraminic acid derivative.

  DOI：

  10.1248/cpb.36.4976