Acridine-3,4,6-triamine | 500574-45-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: Acridine-3,4,6-triamine
• CAS: 500574-45-8
• 化学式: C₁₃H₁₂N₄
• 分子量: 224.265
• InChiKey: PJLFZFHWMFCRHQ-UHFFFAOYSA-N

物化性质

• 沸点：
  556.5±35.0 °C(Predicted)
• 密度：
  1.421±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  91
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,10-邻二氮杂菲-5,6-二酮 、 Acridine-3,4,6-triamine 以 乙醇 为溶剂， 反应 1.0h， 以89%的产率得到15-amino-dipyrido[3,2-a:2',3'-c]quinolino[2,3-h]phenazine
  参考文献：
  名称：

  Regioselective synthesis of angular nitrogen polyheterocycles: dipyrido[3,2-a:2′,3′-c]quinolino[2,3-h]phenazines

  摘要：

  Novel polyaza heterocycles, dipyrido[3,2-a:2',3'-c]quinolino[2,3-h]phenazines, were synthesized via a regiocontrolled condensation between 5,6-phendione and 3,4-diaminoacridine derivatives. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)01900-7
• 作为产物：
  描述：

  原黄素 在 氟硼酸钠 、 sodium dithionite 作用下， 以 甲醇 、 N,N-二甲基甲酰胺 为溶剂， 反应 5.0h， 生成 Acridine-3,4,6-triamine
  参考文献：
  名称：

  Regioselective synthesis of angular nitrogen polyheterocycles: dipyrido[3,2-a:2′,3′-c]quinolino[2,3-h]phenazines

  摘要：

  Novel polyaza heterocycles, dipyrido[3,2-a:2',3'-c]quinolino[2,3-h]phenazines, were synthesized via a regiocontrolled condensation between 5,6-phendione and 3,4-diaminoacridine derivatives. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)01900-7

文献信息

• METHOD AND KIT FOR ASSESSING VIABLE CELLS
  申请人：ChemoMetec A/S

  公开号：US20160131658A1

  公开（公告）日：2016-05-12

  The present invention provides simple, rapid methods and procedures for analyzing cells, hereunder quantitative and qualitative assessment of cells, such as viability. The present invention relates to the use of various optionally substituted reporter compounds particularly detectable upon their reaction with thiol-containing species present in higher concentrations in intact (e.g., living) cells than in non-intact (e.g., dead, stressed and apoptotic) cells. The present invention also relates to the use of various optionally substituted reporter compounds particularly detectable upon their reaction with species present in intact and/or non-intact cells. Moreover, the present invention relates to the use of measuring techniques and/or instruments coupled with the use of various optionally substituted reporter compounds. The invention further relates to compositions used in methods for analyzing cells, such as a composition comprising N-(7-dimethylamino-4-methyl-3-coumarinyl)-maleimide (DACM).