| 945681-75-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• CAS: 945681-75-4
• 化学式: C₁₁H₁₇NO₅
• 分子量: 243.26
• InChiKey: VVQHFWVNSHSEMK-VFCFLDTKSA-N

反应信息

• 作为反应物：
  描述：

  在 sodium periodate 作用下， 以 甲醇 、 水 为溶剂， 反应 3.0h， 生成
  参考文献：
  名称：

  Synthesis of 2,3‐Dihydroxy‐1‐Epilupinine

  摘要：

  The 1,3- dipolar cycloaddition of unsaturated D- threo- hexaldonolactone 3 and a six- membered cyclic nitrone 11 led to a single adduct 15, which could be transformed into ( 1S, 2S, 3S, 9aS)- 2,3- dihydroxy- 1- hydroxymethyl- quinolizidine 28 related to epilupinine via a reaction sequence involving rearrangement of the six- membered lactone ring into a five- membered one, removal of the terminal carbon atom from the sugar chain, cleavage of the N- O bond, and the intramolecular alkylation of the nitrogen atom.

  DOI：

  10.1080/07328300701351540
• 作为产物：
  描述：

  [(1R,2R,5R,6S,7S)-6-acetyloxy-3-oxo-4,8-dioxa-9-azatricyclo[7.4.0.02,7]tridecan-5-yl]methyl acetate 在 sodium carbonate 作用下， 以 甲醇 为溶剂， 反应 0.67h， 以91%的产率得到
  参考文献：
  名称：

  Synthesis of 2,3‐Dihydroxy‐1‐Epilupinine

  摘要：

  The 1,3- dipolar cycloaddition of unsaturated D- threo- hexaldonolactone 3 and a six- membered cyclic nitrone 11 led to a single adduct 15, which could be transformed into ( 1S, 2S, 3S, 9aS)- 2,3- dihydroxy- 1- hydroxymethyl- quinolizidine 28 related to epilupinine via a reaction sequence involving rearrangement of the six- membered lactone ring into a five- membered one, removal of the terminal carbon atom from the sugar chain, cleavage of the N- O bond, and the intramolecular alkylation of the nitrogen atom.

  DOI：

  10.1080/07328300701351540