2-m-Nitrobenzoylfuran | 59728-82-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-m-Nitrobenzoylfuran
• 英文别名: furan-2-yl-(3-nitro-phenyl)-methanone；Furan-2-yl-(3-nitrophenyl)methanone
• CAS: 59728-82-4
• 化学式: C₁₁H₇NO₄
• 分子量: 217.181
• InChiKey: NEQNUICGVSSOSE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  76
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  间硝基苯甲酸 在 三氯化铝 、 氯化亚砜 作用下， 生成 2-m-Nitrobenzoylfuran
  参考文献：
  名称：

  五元单杂环苯甲酰基衍生物的红外和核磁共振特性及芳香度指数的测定

  摘要：

  二苯甲酮，2- benzoylthiophenes，2- benzoylpyrroles和2- benzoylfurans，其在具有取代基的米-和p苯甲酰基环的位上制备并在0.1，得到它们的红外和核磁共振光谱中号氯仿d溶液。将每个系列的化学位移值与哈米特取代基参数作图，以得到良好的相关性，但邻位-Hs和-Cs除外。斜率以及化学位移的差异为芳香性指数提供了一组有意义的值。

  DOI：

  10.1002/jhet.5570400504

文献信息

• [EN] OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS<br/>[FR] DERIVES D'OXAZOLIDINONES EN TANT QU'AGENTS ANITMICROBIENS
  申请人：RANBAXY LAB LTD

  公开号：WO2004069816A1

  公开（公告）日：2004-08-19

  The present invention relates to certain substituted phenyl oxazolidinones of the formula h wherein T is a ring and to the processes for the synthesis of the same. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bactericides spp. and Clostridia spp. species, and acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.

  本发明涉及某些带有取代基的苯基噁唑烷酮，其化学式为h，其中T是一个环，并涉及其合成过程。这些化合物是有用的抗微生物剂，对许多人类和兽医病原体有效，包括革兰氏阳性厌氧细菌，如多重耐药葡萄球菌、链球菌和肠球菌，以及厌氧生物，如杆菌属和梭菌属物种，以及耐酸生物，如结核分枝杆菌、分枝杆菌和结核分枝杆菌、分枝杆菌和分枝杆菌属。
• Oxazolidinone derivatives as pontential antimicrobials
  申请人：——

  公开号：US20040242591A1

  公开（公告）日：2004-12-02

  The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bacteroides spp. and Clostridium spp. species, and acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.

  本发明涉及某些取代苯基噁唑啉酮以及其合成的方法。本发明还涉及含有本发明化合物作为抗微生物药物的制剂。这些化合物是有用的抗微生物剂，对许多人类和兽医病原体有效，包括革兰氏阳性的需氧菌，如多重耐药葡萄球菌、链球菌和肠球菌，以及厌氧菌，如Bacteroides属和Clostridium属物种，以及酸性快速菌，如结核分枝杆菌、埃及分枝杆菌和分枝杆菌属。
• OXAZOLIDINONE DERIVATIVES AS POTENTIAL ANTIMICROBIALS
  申请人：RANBAXY LABORATORIES, LTD.

  公开号：EP1409464A1

  公开（公告）日：2004-04-21
• OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS
  申请人：RANBAXY LABORATORIES, LTD.

  公开号：EP1594852A1

  公开（公告）日：2005-11-16
• [EN] OXAZOLIDINONE DERIVATIVES AS POTENTIAL ANTIMICROBIALS<br/>[FR] DERIVES D'OXAZOLIDINONE UTILISES COMME ANTIMICROBIENS POTENTIELS
  申请人：RANBAXY LAB LTD

  公开号：WO2003008389A1

  公开（公告）日：2003-01-30

  The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bacteroides spp. and Clostridium spp. species, and acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.