N'-(quinolin-2-ylmethylene)-4-(dimethylamino)benzohydrazide | 676243-31-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N'-(quinolin-2-ylmethylene)-4-(dimethylamino)benzohydrazide
• CAS: 676243-31-5
• 化学式: C₁₉H₁₈N₄O
• 分子量: 318.378
• InChiKey: METCMYPQJOIZPJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.06
• 重原子数：
  24.0
• 可旋转键数：
  4.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  57.59
• 氢给体数：
  1.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  N'-(quinolin-2-ylmethylene)-4-(dimethylamino)benzohydrazide 、 水 、 copper(II) nitrate 以 乙醇 为溶剂， 生成
  参考文献：
  名称：

  Quinoline-based colorimetric chemosensor for Cu2+: Cu2+-induced deprotonation leading to color change

  摘要：

  A quinoline-based colorimetric chemosensor (QDB) for Cu2+ was synthesized by coupling quinoline-2-carbaldehyde with 4-(dimethylamino)benzohydrazide. Although most transition metal cations can cause redshifts in the UV-vis spectrum of QDB, the response of the chemosensor for Cu2+ can be easily distinguished because it exhibits the largest redshift together with a color change from colorless to red in response to Cu2+. Other metal ions have no effect on the specific response of QDB to Cu2+. The significant redshift and color change were attributed to Cu2+-induced deprotonation of NH in the sensor. (C) 2013 En-Ju Wang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  DOI：

  10.1016/j.cclet.2013.08.002
• 作为产物：
  描述：

  喹啉-2-甲醛 、 对二甲氨基苯甲酰肼 以 甲醇 为溶剂， 反应 10.0h， 以63%的产率得到N'-(quinolin-2-ylmethylene)-4-(dimethylamino)benzohydrazide
  参考文献：
  名称：

  Quinoline-based colorimetric chemosensor for Cu2+: Cu2+-induced deprotonation leading to color change

  摘要：

  A quinoline-based colorimetric chemosensor (QDB) for Cu2+ was synthesized by coupling quinoline-2-carbaldehyde with 4-(dimethylamino)benzohydrazide. Although most transition metal cations can cause redshifts in the UV-vis spectrum of QDB, the response of the chemosensor for Cu2+ can be easily distinguished because it exhibits the largest redshift together with a color change from colorless to red in response to Cu2+. Other metal ions have no effect on the specific response of QDB to Cu2+. The significant redshift and color change were attributed to Cu2+-induced deprotonation of NH in the sensor. (C) 2013 En-Ju Wang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  DOI：

  10.1016/j.cclet.2013.08.002