(4R,5S,6S)-4-[(1S,2R,3R)-7-Benzenesulfonyl-1-((2S,4S,5R,6R)-4-methoxy-6-methyl-5-triethylsilanyloxy-tetrahydro-pyran-2-yloxy)-3-methyl-2,3-bis-triethylsilanyloxy-heptyl]-2,2-di-tert-butyl-6-isopropenyl-5-methyl-[1,3,2]dioxasilinane | 129986-52-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (4R,5S,6S)-4-[(1S,2R,3R)-7-Benzenesulfonyl-1-((2S,4S,5R,6R)-4-methoxy-6-methyl-5-triethylsilanyloxy-tetrahydro-pyran-2-yloxy)-3-methyl-2,3-bis-triethylsilanyloxy-heptyl]-2,2-di-tert-butyl-6-isopropenyl-5-methyl-[1,3,2]dioxasilinane
• CAS: 129986-52-3
• 化学式: C₅₄H₁₀₄O₁₀SSi₄
• 分子量: 1057.82
• InChiKey: CZBTVWSBHIRWHW-VKIKBPRDSA-N

反应信息

• 作为产物：
  描述：

  <4R-<4α(1R^*,2R^*,3R^*),5α,6α>>-<1-<2,2-bis(1,1-dimethylethyl)-5-methyl-6-(1-methylethenyl)-1,3-dioxa-2-silacycyclohex-4-yl>-2,3-bis<(triethylsilyl)oxy>-3-methyl-7-(phenylthio)heptyl> 2,6-dideoxy-3-O-methyl-4-O-(triethylsilyl)-β-D-ribo-hexopyr... 在 四氧化锇 N-甲基吗啉 作用下， 以 水 、 丙酮 为溶剂， 反应 0.33h， 以93%的产率得到(4R,5S,6S)-4-[(1S,2R,3R)-7-Benzenesulfonyl-1-((2S,4S,5R,6R)-4-methoxy-6-methyl-5-triethylsilanyloxy-tetrahydro-pyran-2-yloxy)-3-methyl-2,3-bis-triethylsilanyloxy-heptyl]-2,2-di-tert-butyl-6-isopropenyl-5-methyl-[1,3,2]dioxasilinane
  参考文献：
  名称：

  A mild, osmium tetraoxide-catalyzed method for the oxidation of sulfides to sulfones

  摘要：

  Osmium tetraoxide has been demonstrated to be a highly efficient catalyst for the chemoselective oxidation of a variety of sulfides to the corresponding sulfones. Tertiary amine catalysis appears to play a key role in the reaction.

  DOI：

  10.1016/s0040-4039(00)93423-3