3-(4-hydroxy-3,5-dimethoxyphenyl)-2-[1-(4-hydroxy-3,5-dimethoxyphenyl)-acetyl]-(E)-2-propenoic acid | 927819-54-3

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• 英文名称: 3-(4-hydroxy-3,5-dimethoxyphenyl)-2-[1-(4-hydroxy-3,5-dimethoxyphenyl)-acetyl]-(E)-2-propenoic acid
• CAS: 927819-54-3
• 化学式: C₂₁H₂₂O₉
• 分子量: 418.4
• InChiKey: PLSIZQVCZHVOEO-WLRTZDKTSA-N

反应信息

• 作为产物：
  描述：

  芥子酸 在 双氧水 、 Momordica charantia peroxidase 作用下， 以 丙酮 为溶剂， 反应 4.0h， 以16 mg的产率得到3-(4-hydroxy-3,5-dimethoxy)-2-[2,5-bis(4-hydroxy-3,5-dimethoxy)-4-[3-(4-hydroxy-3,5-dimethoxy)-[(Z)-2-carboxyethenyl]-2-yl]furan-3-yl]-(Z)-2-propenoic acid methyl ester
  参考文献：
  名称：

  Biotransformation of Sinapic Acid Catalyzed by Momordica charantia Peroxidase

  摘要：

  Biotransformation of sinapic acid (1) with H2O2/Momordica charantia peroxidase, which exists in the widely used food M. charantia, at pH 5.0, 43 degrees C, in the presence of acetone resulted in six compounds, including four new compounds. Compound 2 was the first isolation of a new unique sinapic acid tetrameric derivate, which is formed by peroxidase catalysis in vitro. Besides 2, three other new sinapic acid dimers, 3-5 have also been isolated. Their structures were established on the basis of spectroscopic data. Compound 5 showed a stronger antioxidative activity than the parent sinapic acid (1). Compounds 4 and 5 significantly inhibited the growth of HL-60 cell at the concentration of 10(-5) mol/L.

  DOI：

  10.1021/jf0628072