1,1,1-Trifluoro-4-phenylpent-3-en-2-ol | 89536-83-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂醇
• 英文名称: 1,1,1-Trifluoro-4-phenylpent-3-en-2-ol
• CAS: 89536-83-4
• 化学式: C₁₁H₁₁F₃O
• 分子量: 216.2
• InChiKey: LSHZBKBYSXEMOA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Process for preparing a beta-(fluoroalkyl or fluoroalkenyl)-beta-hydroxyalkyne and an alpha-(fluoroalkyl or fluoroalkenyl)-allyl alcohol thereof
  申请人：Daikin Kogyo Co., Ltd.

  公开号：EP0118890A1

  公开（公告）日：1984-09-19

  A process for preparing a β-(fluoroalkyl or fluoroalkenyl)-β-hydroxyalkyne represented by the formula wherein Rf represents a fluoroalkyl or fluoroalkenyl group and R represents an aliphatic or aromatic group, comprising reacting an alkyne represented by the formula wherein R is the same as defined above with a fluorine containing aldehyde represented by the formula wherein Rf is the same as defined above in the presence of catalyst under ultrasonic irradiation. A process for preparing an a-(fluoroalkyl or fluoroalkenyl) allyl alcohol represented by the formula ; wherein Rf represents a fluoroalkyl or fluoroalkenyl group, R represents an aliphatic or aromatic group and R' represents a hydrogen atom or an aliphatic group, comprising (1) reacting a β-(fluoroalkyl or fluoroalkenyl)-β-hydroxyalkyne represented by the formula wherein Rf and R are respectively the same as defined above with a isobutylmagnesium halide represented by the formula wherein X represents a halogen atom, and (2) reacting the reaction mixture thus obtained above with a halide represented by the formula wherein X' represents a halogen atom and R' is the same as defined above.

  一种制备β-(氟烷基或氟烯基)-β-羟基炔的工艺，由式表示 其中 Rf 代表氟烷基或氟烯基，R 代表脂肪族或芳香族基团，包括反应式如下代表的炔烃 式中 R 与上式定义相同的含氟醛反应 其中 Rf 与上述定义相同，在催化剂存在下，在超声波辐照下反应。 一种制备由式...代表的 a-(氟烷基或氟烯基)烯丙基醇的工艺； 其中 Rf 代表氟烷基或氟烯基，R 代表脂肪族或芳香族基团，R'代表氢原子或脂肪族基团，该工艺包括 (1) 反应式中β-(氟烷基或氟烯基)-β-羟基炔 其中 Rf 和 R 分别与上式所定义的异丁基卤化镁相同 式中 X 代表卤素原子，以及 (2) 将上述反应混合物与式中代表的卤化物反应 其中 X'代表卤素原子，R'与上述定义相同。
• US4532020A
  申请人：——

  公开号：US4532020A

  公开（公告）日：1985-07-30