(2S,3S,4R,5S) 3,5-diacetoxy-2,4-isopropylidenedioxy-4-methyl-5-phenylpentane | 156746-40-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S,3S,4R,5S) 3,5-diacetoxy-2,4-isopropylidenedioxy-4-methyl-5-phenylpentane
• CAS: 156746-40-6
• 化学式: C₁₉H₂₆O₆
• 分子量: 350.412
• InChiKey: KZIJFPFJXXRVAS-ZQINRCPSSA-N

物化性质

• 沸点：
  411.1±45.0 °C(predicted)
• 密度：
  1.14±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

反应信息

• 作为反应物：
  描述：

  (2S,3S,4R,5S) 3,5-diacetoxy-2,4-isopropylidenedioxy-4-methyl-5-phenylpentane 在 sodium hydroxide 作用下， 以 甲醇 为溶剂， 反应 1.0h， 以80%的产率得到(2S,3S,4R,5S) 3,5-dihydroxy-2,4-isopropylidenedioxy-4-methyl-5-phenylpentane
  参考文献：
  名称：

  On the asymmetric dihydroxylation of (2S,3R) 5-phenylpent-4-en-2,3-diol derivatives

  摘要：

  Sharpless OsO4 asymmetric dihydroxylation of derivatives of the unsaturated (2S,3R) diols 2 affords products 7a,b and 10 and the diastereoisomers 8a,b and 11, respectively, in ratios depending upon the nature of the ligand (dihydroquinine and dihydroquinidine 4-chlorobenzoates), the mode of hydroxyl groups protection and the pattern of double bond substitution.

  DOI：

  10.1016/s0040-4020(01)90413-2
• 作为产物：
  描述：

  (2S,3R) 2,3-diacetoxy-4-methyl-5-phenylpent-4-ene 在 potassium osmate(VI) 、 dihydroquinine 4-chlorobenzoate 、 potassium carbonate 、 对甲苯磺酸 、 potassium hexacyanoferrate(III) 作用下， 以 水 、 丙酮 、 叔丁醇 为溶剂， 反应 0.5h， 生成 (2S,3S,4R,5S) 3,5-diacetoxy-2,4-isopropylidenedioxy-4-methyl-5-phenylpentane
  参考文献：
  名称：

  On the asymmetric dihydroxylation of (2S,3R) 5-phenylpent-4-en-2,3-diol derivatives

  摘要：

  Sharpless OsO4 asymmetric dihydroxylation of derivatives of the unsaturated (2S,3R) diols 2 affords products 7a,b and 10 and the diastereoisomers 8a,b and 11, respectively, in ratios depending upon the nature of the ligand (dihydroquinine and dihydroquinidine 4-chlorobenzoates), the mode of hydroxyl groups protection and the pattern of double bond substitution.

  DOI：

  10.1016/s0040-4020(01)90413-2