Sodium; (E)-3-(3,4-bis-methoxymethoxy-phenyl)-acrylate | 145904-56-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: Sodium; (E)-3-(3,4-bis-methoxymethoxy-phenyl)-acrylate
• CAS: 145904-56-9
• 化学式: C₁₃H₁₅O₆*Na
• 分子量: 290.248
• InChiKey: QCRFAIRQXCFNSB-CVDVRWGVSA-M

反应信息

• 作为反应物：
  描述：

  4-(3-Bromo-2-hydroxypropyl)catechol di(methoxymethyl)ether 、 Sodium; (E)-3-(3,4-bis-methoxymethoxy-phenyl)-acrylate 以 六甲基磷酰三胺 、 N,N-二甲基甲酰胺 为溶剂， 反应 8.0h， 以91.3%的产率得到(E)-3-(3,4-Bis-methoxymethoxy-phenyl)-acrylic acid 3-(3,4-bis-methoxymethoxy-phenyl)-2-hydroxy-propyl ester
  参考文献：
  名称：

  Isolation and Synthesis of a New Bio-antimutagen, Petasiphenol, from Scapes ofPetasites japonicum

  摘要：

  A new bio-antimutagen, petasiphenol [3-(3,4-dihydroxyphenyl)-2-oxopropyl caffeate] (1) was isolated from scapes of Petasites japonicum (AD50 =95μg/ml against UV-induced mutagenic E. coli WP2 B/r Trp−. Petasiphenol (1) and its isomer (2) were synthesized. The activity of 1 was observed in the presence of soybean oil (glyceride), although the isomer (2) did not show any activity in doses up to 300, μg/ml.

  DOI：

  10.1271/bbb.56.1773