1-(5-methoxy-2,4-dimethyl-phenyl)-ethanone | 53005-51-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(5-methoxy-2,4-dimethyl-phenyl)-ethanone
• 英文别名: 1-(5-Methoxy-2,4-dimethyl-phenyl)-aethanon；5'-Methoxy-2',4'-dimethylacetophenone；1-(5-methoxy-2,4-dimethylphenyl)ethanone
• CAS: 53005-51-9
• 化学式: C₁₁H₁₄O₂
• 分子量: 178.231
• InChiKey: PCVKVXKLOASFDG-UHFFFAOYSA-N

物化性质

• 沸点：
  266.6±35.0 °C(Predicted)
• 密度：
  1.004±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-(5-methoxy-2,4-dimethyl-phenyl)-ethanone 在 盐酸 、 amalgamated zinc 作用下， 生成 5-ethyl-2,4-dimethyl-anisole
  参考文献：
  名称：

  v. Auwers; Mauss, Chemische Berichte, 1928, vol. 61, p. 1502

  摘要：

  DOI：
• 作为产物：
  描述：

  2,4-二甲基-1-甲氧基苯 、 乙酰氯 在 二硫化碳 、 三氯化铝 作用下， 生成 1-(5-methoxy-2,4-dimethyl-phenyl)-ethanone
  参考文献：
  名称：

  v. Auwers; Mauss, Chemische Berichte, 1928, vol. 61, p. 1502

  摘要：

  DOI：

文献信息

• Modulation of Bacterial Quorum Sensing with Synthetic Ligands
  申请人：Blackwell Helen E.

  公开号：US20080312319A1

  公开（公告）日：2008-12-18

  The present invention provides compounds and methods for modulation of the quorum sensing of bacteria. In an embodiment, the compounds of the present invention are able to act as replacements for naturally occurring bacterial quorum sensing ligands in a ligand-protein binding system; that is, they imitate the effect of natural ligands and produce an agonistic effect. In another embodiment, the compounds of the present invention are able to act in a manner which disturbs or inhibits the naturally occurring ligand-protein binding system in quorum sensing bacteria; that is, they produce an antagonistic effect. The compounds of the present invention comprise N-acylated-homoserine lactones (AHLs) comprised of a wide range of acyl groups.