2-Dimethoxymethyl propionitril | 50744-69-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Dimethoxymethyl propionitril
• 英文别名: β,β-dimethoxy-isobutyronitrile；3,3-Dimethoxy-2-methylpropanenitrile
• CAS: 50744-69-9
• 化学式: C₆H₁₁NO₂
• 分子量: 129.159
• InChiKey: HARZOGJXMSZKTJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  42.2
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  aminopentanal diethyl acetal 、 2-Dimethoxymethyl propionitril 在 镍 氢气 作用下， 以 甲醇 为溶剂， 反应 3.56h， 生成 氨基丁醛二甲基缩醛
  参考文献：
  名称：

  Self- and diol reactive formaldehyde-free crosslinking monomers and

  摘要：

  以下化合物的化学式：##STR1## 其中R是一个具有使氮原子电子亏损的官能团的C.sub.3-C.sub.24烯烃不饱和有机基团，烯烃不饱和官能团是可聚合的，R.sup.1是氢或C.sub.1-C.sub.4烷基基团，或者R和R.sup.1与氮原子一起可以形成具有使氮原子电子亏损的官能团的烯烃不饱和5至7元环，烯烃不饱和官能团是可聚合的，R.sup.2和R.sup.3是氢、C.sub.1-C.sub.4烷基或酰基基团，或者R.sup.2和R.sup.3一起是C.sub.1-C.sub.4烷基撑链基团，R.sup.4是氢或C.sub.1-C.sub.4烷基、酰基、酯、酰胺或酸基团，n是1到10的整数，当R为(meth)acryloyl，R.sup.2和R.sup.3为甲基，R.sup.1和R.sup.4为氢时，n不为1。

  公开号：

  US04864055A1
• 作为产物：
  描述：

  2-二甲氧基甲基-丙烯腈 在 甲醇 、 palladium on activated charcoal 作用下， 生成 2-Dimethoxymethyl propionitril
  参考文献：
  名称：

  Monitoring of Partial Pharyngeal Reconstruction

  摘要：

  DOI：

  10.1097/00005537-200203000-00031

文献信息

• Self-and Hydroxyl reactive formaldehyde-free cyclic hemiamidal and
  申请人：Air Products and Chemicals, Inc.

  公开号：US04788288A1

  公开（公告）日：1988-11-29

  A compound represented by the following formula: ##STR1## wherein R is a C.sub.3 -C.sub.24 olefinically unsaturated organic radical having functionality which renders the nitrogen atom electron deficient, the olefinic unsaturation functionality being polymerizable, R.sup.1 is hydrogen or a C.sub.1 -C.sub.4 alkyl radical, or R and R.sup.1 together with the nitrogen atom can form an olefinically unsaturated 5 to 7-member ring which has functionality that renders the nitrogen atom electron deficient and the olefinic unsaturation functionality is polymerizable, R.sup.2 and R.sup.3 are hydrogen, a C.sub.1 -C.sub.4 alkyl or acyl radical, or R.sup.2 and R.sup.3 together are a C.sub.2 -C.sub.4 alkylene group, R.sup.4 is hydrogen or a C.sub.1 -C.sub.4 alkyl, acyl, ester, amide or acid group, and n is an integer from 1 to 10, provided n is not 1 when R is (meth)acryloyl, R.sup.2 and R.sup.3 are methyl and R.sup.1 and R.sup.4 are hydrogen. Under acidic conditions the above compounds having R.sup.1 =hydrogen afford cyclic hemiamidals and hemiamide ketals of the following formula ##STR2##

  以下化合物的化学式：##STR1## 其中R是具有使氮原子电子不足的官能团的C.sub.3-C.sub.24烯丙基不饱和有机基，烯丙基不饱和官能团可聚合，R.sup.1是氢或C.sub.1-C.sub.4烷基基团，或R和R.sup.1与氮原子一起可以形成具有使氮原子电子不足的烯丙基不饱和5至7环成员环，烯丙基不饱和官能团可聚合，R.sup.2和R.sup.3是氢，C.sub.1-C.sub.4烷基或酰基基团，或R.sup.2和R.sup.3一起是C.sub.2-C.sub.4烷基基团，R.sup.4是氢或C.sub.1-C.sub.4烷基，酰基，酯，酰胺或酸基团，n是1至10的整数，当R为（甲基）丙烯酰基，R.sup.2和R.sup.3为甲基，R.sup.1和R.sup.4为氢时，n不为1。在酸性条件下，具有R.sup.1 =氢的上述化合物会产生如下化合物的环状半胺和半胺酮：##STR2##
• Resin Composition
  申请人：Masuda Gen

  公开号：US20070244241A1

  公开（公告）日：2007-10-18

  Disclosed is a resin composition wherein dispersibility of a modifying agent such as an inorganic substance is improved. The acid resistance of this resin composition is not deteriorated even when a modifying agent is blended therein. Specifically, the resin composition includes a base material having a cyano group-containing organic layer and an organic resin. This resin composition is extremely excellent in acid resistance when compared with organic resins which use a base material having an organic layer not containing a cyano group.

  公开了一种树脂组合物，其中改性剂（如无机物质）的分散性得到改善。即使混合了改性剂，这种树脂组合物的耐酸性也不会恶化。具体来说，该树脂组合物包括具有含氰基有机层和有机树脂的基材。与基材不含氰基的有机层的有机树脂相比，该树脂组合物的耐酸性非常优秀。
• METHOD FOR THE SYNTHESIS OF AN AMINO ACETAL
  申请人：Loh Teck Peng

  公开号：US20130165682A1

  公开（公告）日：2013-06-27

  The present invention relates to a method for the synthesis of an α amino acetal, comprising (i) oxidizing a tertiary amine in the presence of a copper catalyst, at least one oxidant and a solvent, or (ii) reacting a secondary amine and an aliphatic aldehyde in the presence of a copper catalyst, at least one oxidant and a solvent.

  本发明涉及一种合成α氨基缩醛的方法，包括（i）在铜催化剂、至少一种氧化剂和溶剂的存在下氧化三级胺，或（ii）在铜催化剂、至少一种氧化剂和溶剂的存在下反应二级胺和脂肪族醛。
• Process for preparing 4-amino-5-dialkoxymethylpyrimidine derivatives
  申请人：UBE INDUSTRIES, LTD.

  公开号：EP0103126A1

  公开（公告）日：1984-03-21

  There are disclosed a process for preparing a 4-amino-5-dialkoxymethylpyrimidine derivative of the formula: which comprises subjecting a propanenitrile derivative represented by the formula (I) or (II) to reaction with an amidine of the formula wherein all the R1 to R6 are as defined in the specification; and a novel starting compound of the above formula (II) useful for the process.

  本发明公开了一种制备式 4-氨基-5-二烷氧基甲基嘧啶衍生物的工艺： 其中包括将式(I)或(II)所代表的丙腈衍生物 与式 其中所有 R1 至 R6 均如说明书中所定义；以及对该工艺有用的上述式 (II) 的新型起始化合物。
• Polymers of self- and hydroxyl reactive formaldehyde-free cyclic hemiamidal and hemiamide ketal crosslinking monomers
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：EP0211432A2

  公开（公告）日：1987-02-25

  A compound represented by the following formula: wherein R is a C3-C21 olefinically unsaturated organic radical having functionality which renders the nitrogen atom electron deficient, the olefinic unsaturation functionality being polymerizable, R' is hydrogen or a C1-C4 alkyl radical, or R and R' together with the nitrogen atom can form an olefinically unsaturated 5 to 7-member ring which has functionality that renders the nitrogen atom electron deficient and the olefinic unsaturation functionality is polymerizable, R2 and R3 are hydrogen, a C1-C4 alkyl or acyl radical, or R2 and R3 together are a C2-C4 alkylene group, R4 is hydrogen or a C1-C4 alkyl, acyl, ester, amide or acid group, and n is an integer from 1 to 10, provided n is not 1 when R is (meth)acryloyl, R2 and R3 are methyl and R' and R4 are hydrogen. Under acidic conditions the above compounds in which R' is hydrogen afford cyclic hemiamidals and hemiamide ketals of the following formula: The dialkyl acetal and ketal compounds and the cyclic hemiamidal and hemiamide ketal compounds can be homopolymerized or polymerized with other copolymerizable monomers.

  下式所代表的化合物： 其中 R 是 C3-C21 烯烃不饱和有机基，具有使氮原子缺电子的官能度，烯烃不饱和官能度可聚合、 R' 是氢或 C1-C4 烷基，或 R 和 R'与氮原子一起可形成烯烃不饱和 5 至 7 元环，该环具有使氮原子缺电子的官能度，且烯烃不饱和官能度可聚合、 R2 和 R3 是氢、C1-C4 烷基或酰基，或 R2 和 R3 合在一起是一个 C2-C4 烯基、 R4 是氢或 C1-C4 烷基、酰基、酯基、酰胺基或酸基，以及 n 是 1 到 10 的整数，但当 R 是（甲基）丙烯酰基、R2 和 R3 是甲基、R'和 R4 是氢时，n 不是 1。 在酸性条件下，R'为氢的上述化合物可生成下式的环半酰胺和半酰胺酮： 二烷基缩醛和缩酮化合物以及环半酰胺和半酰胺缩酮化合物可以均聚或与其他可共聚单体聚合。