Celestine blue | 1562-90-9

• 物质功能分类: 生物化工 - 生化试剂 - 生物染料
• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: Celestine blue
• 英文别名: [7-(diethylamino)-3,4-dioxo-10H-phenoxazine-1-carbonyl]azanium;chloride
• CAS: 1562-90-9
• 化学式: C17H18N3O4.Cl
• 分子量: 363.8
• InChiKey: REPMZEQSQQAHJR-UHFFFAOYSA-N

物化性质

• 熔点：
  227-230 °C

计算性质

• 辛醇/水分配系数(LogP)：
  -2.88
• 重原子数：
  25
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  105
• 氢给体数：
  3
• 氢受体数：
  7

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S22,S24/25
• 危险类别码：
  R36/37/38
• WGK Germany：
  3
• 海关编码：
  32041200

制备方法与用途

用途 

可代替苏木精，用于显微镜或其它用途。

用途 

生物染色剂，用于核细胞组织和结缔组织染色。

文献信息

• Methods for coating surfaces with antimicrobial agents
  申请人：The Board of Regents of the University of Texas System

  公开号：US10589003B2

  公开（公告）日：2020-03-17

  Disclosed are methods for coating or impregnating a surface with an antimicrobial agent that involve contacting the surface with a composition that includes an antimicrobial agent and a solvent, and curing the surface by applying heat. Also disclosed are methods for reducing the risk of development or progression of an infection in a subject in need of a medical device, that involve coating or impregnating a surface of the medical device with an antimicrobial agent and then curing the surface by applying heat, wherein the risk of development or progression of an infection is reduced.

  本发明公开了用抗菌剂涂覆或浸渍表面的方法，包括用包括抗菌剂和溶剂的组合物接触表面，并通过加热固化表面。还公开了降低需要使用医疗器械的受试者发生或恶化感染风险的方法，包括用抗菌剂涂覆或浸渍医疗器械表面，然后通过加热固化表面，从而降低发生或恶化感染的风险。
• Counterstains for a biological sample
  申请人：Key Marc

  公开号：US10718694B2

  公开（公告）日：2020-07-21

  The present disclosure relates to counterstains for staining a biological sample on a single slide in preparation for microscopic examination. The counterstains are used to analyze the sample on the single slide using both brightfield and fluorescent illumination. The counterstains can identify both morphological details and molecular structures within the cells contained in the sample. The counterstains can be used in conjunction with other molecular stains.

  本公开涉及用于在单张载玻片上对生物样本进行染色以备显微镜检查的反染色剂。使用明视野和荧光照明对单张载玻片上的样本进行分析。反印迹可以识别样本中细胞的形态细节和分子结构。反印迹可与其他分子染色法结合使用。
• Ultralow range fluorometer calibration
  申请人：Ecolab USA Inc.

  公开号：US10852235B2

  公开（公告）日：2020-12-01

  A fluorometer may be used to measure ultralow concentrations of fluorescing species, such as ultralow concentrations of fluorescent tracer passing through a reverse osmosis membrane into a permeate stream. In some examples, the fluorometer may be recalibrated by resetting some but not all of the calibration parameters used to determine the concentration of fluorescent tracer in the permeate based on the measured fluorescent response of the fluorometer. For example, an intercept of a calibration curve may be reset or recalibrated for the fluorometer in situ, potentially providing significant accuracy improvements even though the fluorometer has not undergone a full recalibration.

  荧光计可用于测量超低浓度的荧光物质，例如穿过反渗透膜进入渗透液流的超低浓度荧光示踪剂。在某些示例中，可以根据荧光计测得的荧光响应，通过重新设置用于确定渗透液中荧光示踪剂浓度的部分而非全部校准参数，对荧光计进行重新校准。例如，校准曲线的截距可就地重设或重新校准荧光计，即使荧光计没有经过全面的重新校准，也能显著提高精度。
• Tetrazole based corrosion inhibitors
  申请人：ECOLAB USA INC.

  公开号：US10899721B2

  公开（公告）日：2021-01-26

  Disclosed are corrosion inhibitor compounds and compositions useful for preventing or inhibiting corrosion of surfaces found in cooling water applications. In some embodiments, the surfaces may include mild steel, aluminum, brass, copper, galvanized steel, a copper alloy, admirality brass, or any combination thereof. Also disclosed are methods of using the compounds and compositions as corrosion inhibitors. In some embodiments, the corrosion inhibitor compounds and compositions are used in cooling water applications.

  所公开的缓蚀剂化合物和组合物可用于防止或抑制冷却水应用中表面的腐蚀。在某些实施方案中，表面可包括低碳钢、铝、黄铜、铜、镀锌钢、铜合金、钦佩黄铜或它们的任意组合。此外，还公开了将化合物和组合物用作腐蚀抑制剂的方法。在某些实施方案中，缓蚀剂化合物和组合物用于冷却水应用。
• Method of tracing drains
  申请人：——

  公开号：US20030071212A1

  公开（公告）日：2003-04-17

  A method of tracing drains using non-toxic fluorescent tracers is described and claimed.

  描述并声称了一种使用无毒荧光示踪剂追踪排水沟的方法。

表征谱图