2-(4-bromo-2-vinylphenoxy)-1-phenylethanone | 1191064-89-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(4-bromo-2-vinylphenoxy)-1-phenylethanone
• CAS: 1191064-89-7
• 化学式: C₁₆H₁₃BrO₂
• 分子量: 317.182
• InChiKey: YMBVEPMSBWWPKF-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  2-(4-bromo-2-vinylphenoxy)-1-phenylethanone 在 potassium tert-butylate 作用下， 以 四氢呋喃 为溶剂， 以76%的产率得到2-benzoyl-6-bromo-3,4-dihydro-2H-benzopyran
  参考文献：
  名称：

  A novel carbanion-olefin intramolecular cyclization: synthesis of substituted 2-aroyl-3,4-dihydro-2H-benzopyrans from salicylaldehydes

  摘要：

  Utilization of a novel carbanion-olefin intramolecular 6-endo-trig cyclization reaction to provide 2-aroyl-3,4-dihydro-2H-benzopyrans is described. Through a sequence of a Wittig reaction, O-alkylation, and carbanion-olefin intramolecular cyclization, salicylaldehydes were converted into a series of new 2-aroyl-3,4-dihydro-2H-benzopyrans in two steps or in one-pot reaction. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.07.132
• 作为产物：
  描述：

  甲基三苯基溴化膦 、 2-溴苯乙酮 、 5-溴水杨醛 在 potassium tert-butylate 作用下， 以 四氢呋喃 为溶剂， 以79%的产率得到2-(4-bromo-2-vinylphenoxy)-1-phenylethanone
  参考文献：
  名称：

  A novel carbanion-olefin intramolecular cyclization: synthesis of substituted 2-aroyl-3,4-dihydro-2H-benzopyrans from salicylaldehydes

  摘要：

  Utilization of a novel carbanion-olefin intramolecular 6-endo-trig cyclization reaction to provide 2-aroyl-3,4-dihydro-2H-benzopyrans is described. Through a sequence of a Wittig reaction, O-alkylation, and carbanion-olefin intramolecular cyclization, salicylaldehydes were converted into a series of new 2-aroyl-3,4-dihydro-2H-benzopyrans in two steps or in one-pot reaction. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.07.132