2-(3,5-dimethylphenoxy)thiazole | 1292836-23-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(3,5-dimethylphenoxy)thiazole
• 英文别名: 2-(3,5-Dimethylphenoxy)-1,3-thiazole
• CAS: 1292836-23-7
• 化学式: C₁₁H₁₁NOS
• 分子量: 205.28
• InChiKey: PBMUGIUROWVHBD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  50.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-溴噻唑 、 3,5-二甲基苯酚 在 六氟磷酸银 、 rhodium(II) acetate dimer 、 N,N-dicyclohexylbenzimidazolium hexafluorophosphate 、 sodium t-butanolate 作用下， 以 甲苯 为溶剂， 反应 24.0h， 以70%的产率得到2-(3,5-dimethylphenoxy)thiazole
  参考文献：
  名称：

  Rhodium(NHC)-Catalyzed O-Arylation of Aryl Bromides

  摘要：

  The first example of the rhodium-catalyzed O-arylation of aryl bromides is reported. While the right combination of rhodium species and N-heterocyclic carbene (NHC) offered an effective catalytic system enabling the arylation to proceed, the choice of NHC was determined to be most important. The developed O-arylation protocol has a wide range of substrate scope, high functional group tolerance, and flexibility allowing a complementary route to either N- or O-arylation depending on the choice of NHC.

  DOI：

  10.1021/ol200603c

文献信息

• PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS
  申请人：BASF SE

  公开号：EP2066643A1

  公开（公告）日：2009-06-10
• [EN] PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS<br/>[FR] PYRIDAZINE-4-YLMETHYL-SULFONAMIDES UTILISÉS EN TANT QUE FONGICIDES ET COMPOSÉS ANTI-ARTHROPODES
  申请人：BASF SE

  公开号：WO2008062012A1

  公开（公告）日：2008-05-29

  [EN] The present invention relates to novel pyridazin- 4 -ylmethyl- sulfonamide compounds (I) and to their N-oxides, their agriculturally acceptable salts and their veterinarily acceptable salts and also to agricultural compositions comprising at least one such compound as active component, and also to their use for controlling harmful fungi. The present invention also relates to a method for controlling arthropod pests.
  [FR] L'invention concerne de nouveaux composés (I) pyridazin- 4 -ylméthyle- sulfonamide et leurs N-oxydes, leurs sels de qualité agricole acceptable et leurs sels de qualité vétérinaire acceptable, ainsi que des compositions agricoles comprenant au moins le composé utilisé en tant que principe actif, ainsi que leur utilisation dans la suppression de champignons néfastes. L'invention concerne également un procédé pour supprimer des arthropodes nuisibles.