3,6-dimethoxy-10-phenylacridin-9(10H)-one | 71642-42-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 3,6-dimethoxy-10-phenylacridin-9(10H)-one
• 英文别名: 3,6-dimethoxy-10-phenyl-10H-acridin-9-one；3,6-dimethoxy-10-phenylacridin-9-one
• CAS: 71642-42-7
• 化学式: C₂₁H₁₇NO₃
• 分子量: 331.371
• InChiKey: AGOLTLHSGCGSLD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.16
• 重原子数：
  25.0
• 可旋转键数：
  3.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  40.46
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  3,6-dimethoxy-10-phenylacridin-9(10H)-one 以 四氢呋喃 、 乙醚 为溶剂， 反应 48.0h， 生成 9-mesityl-3,6-dimethoxy-10-phenylacridin-10-ium tetrafluoroborate
  参考文献：
  名称：

  Acridinium-Based Photocatalysts: A Sustainable Option in Photoredox Catalysis

  摘要：

  The emergence of visible light photoredox catalysis has enabled the productive use of lower energy radiation, leading to highly selective reaction platforms. Polypyridyl complexes of iridium and ruthenium have served as popular photocatalysts in recent years due to their long excited state lifetimes and useful redox windows, leading to the development of diverse photoredox-catalyzed transformations. The low abundances of Ir and Ru in the earth's crust and, hence, cost make these catalysts nonsustainable and have limited their application in industrial-scale manufacturing. Herein, we report a series of novel acridinium salts as alternatives to iridium photoredox catalysts and show their comparability to the ubiquitous [Ir(dF-CF3-ppy)(2)(dtbpy)](PF6).

  DOI：

  10.1021/acs.joc.6b01240
• 作为产物：
  描述：

  2-溴-4-甲氧基苯甲酸 在 铜 、 potassium carbonate 作用下， 以 戊醇 为溶剂， 反应 54.0h， 生成 3,6-dimethoxy-10-phenylacridin-9(10H)-one
  参考文献：
  名称：

  Acridinium-Based Photocatalysts: A Sustainable Option in Photoredox Catalysis

  摘要：

  The emergence of visible light photoredox catalysis has enabled the productive use of lower energy radiation, leading to highly selective reaction platforms. Polypyridyl complexes of iridium and ruthenium have served as popular photocatalysts in recent years due to their long excited state lifetimes and useful redox windows, leading to the development of diverse photoredox-catalyzed transformations. The low abundances of Ir and Ru in the earth's crust and, hence, cost make these catalysts nonsustainable and have limited their application in industrial-scale manufacturing. Herein, we report a series of novel acridinium salts as alternatives to iridium photoredox catalysts and show their comparability to the ubiquitous [Ir(dF-CF3-ppy)(2)(dtbpy)](PF6).

  DOI：

  10.1021/acs.joc.6b01240

文献信息

• GORVIN J. H.; WHALLEY D. P., J. CHEM. SOC. PERKIN TRANS. PART 1, 1979, NO 5, 1364-1370
  作者：GORVIN J. H.、 WHALLEY D. P.

  DOI：——

  日期：——