N-benzoyl-2-aminoethyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside | 1198425-66-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-benzoyl-2-aminoethyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside
• CAS: 1198425-66-9
• 化学式: C₂₃H₂₉NO₁₁
• 分子量: 495.483
• InChiKey: NTLBEBAFZBQMEL-ZFVIQDPVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.52
• 重原子数：
  35.0
• 可旋转键数：
  10.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  152.76
• 氢给体数：
  1.0
• 氢受体数：
  11.0

反应信息

• 作为反应物：
  描述：

  N-benzoyl-2-aminoethyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside 在 甲醇 、 sodium methylate 作用下， 以 1,4-二氧六环 、 甲醇 为溶剂， 反应 1.0h， 以94%的产率得到N-benzoyl-2-aminoethyl β-D-glucopyranoside
  参考文献：
  名称：

  Nanostructured styrenic co-polymers containing glucopyranosyl residues and their functionalization

  摘要：

  Sugar-based co-polymers with saccharidic units in stable cyclic form and nanometric morphologies stabilized through crosslinking, adaptable through specific functionalizations to biochemical interaction studies with copper-containing amine oxidases, were synthesized from appropriate monomers and macromonomers. The most promising nanospherical co-polymer obtained, containing beta-D-glucopyranosidic units, was employed in functionalization reactions with the help of model molecules, achieving useful transformations mainly at the 6-position and to a minor extent at the 2-position of the saccharidic system. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.05.033
• 作为产物：
  描述：

  N-(2-hydroxyethyl)-benzamide 、 β-D-葡萄糖五乙酸酯 在 三氟化硼乙醚 、 水 作用下， 以 二氯甲烷 为溶剂， 反应 24.67h， 以75%的产率得到N-benzoyl-2-aminoethyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside
  参考文献：
  名称：

  Nanostructured styrenic co-polymers containing glucopyranosyl residues and their functionalization

  摘要：

  Sugar-based co-polymers with saccharidic units in stable cyclic form and nanometric morphologies stabilized through crosslinking, adaptable through specific functionalizations to biochemical interaction studies with copper-containing amine oxidases, were synthesized from appropriate monomers and macromonomers. The most promising nanospherical co-polymer obtained, containing beta-D-glucopyranosidic units, was employed in functionalization reactions with the help of model molecules, achieving useful transformations mainly at the 6-position and to a minor extent at the 2-position of the saccharidic system. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.05.033