(2R,3R,4R,5S,6R)-2-((2S,3S,4S,5R,6R)-6-Fluoro-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-pyran-3-ylmethyl)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol | 210634-40-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,3R,4R,5S,6R)-2-((2S,3S,4S,5R,6R)-6-Fluoro-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-pyran-3-ylmethyl)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol
• CAS: 210634-40-5
• 化学式: C₁₃H₂₃FO₉
• 分子量: 342.319
• InChiKey: ZTBAJIYWEILFAJ-VHGSIDFWSA-N

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 (2R,3R,4R,5S,6R)-2-((2S,3S,4S,5R,6R)-6-Fluoro-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-pyran-3-ylmethyl)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol 在 4-二甲氨基吡啶 、 phosphate buffer 、 CGTase 作用下， 生成 acetylated hemi C-maltooctaose 、 acetylated hemi-C-maltotetraose 、 acetylated hemi C-maltohexaose 、 acetylated hemi C-maltohexaose
  参考文献：
  名称：

  Transfer reactions catalyzed by cyclodextrin glucosyltransferase using 4-thiomaltosyl and C-maltosyl fluorides as artificial donors

  摘要：

  Cyclodextrin glycosyltransferase enzyme from Bacillus circulans catalyzed the effective conversion of 4-thio-alpha-maltosyl fluoride into cyclo-alpha-(1-->4)-thiomalto -tetraoside, -pentaoside, -hexaoside and linear hemithiomaltooligosaccharides. However, under the same conditions, C-maltosyl fluoride afforded only linear modified maltotetraose, maltohexaose and maltooctaose in moderate yield. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0008-6215(97)00262-0
• 作为产物：
  描述：

  Acetic acid (2R,3R,4S,5R,6S)-3-acetoxy-6-acetoxymethyl-2-fluoro-5-((2R,3S,4R,5R,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-ylmethyl)-tetrahydro-pyran-4-yl ester 在 sodium methylate 作用下， 以 甲醇 为溶剂， 反应 2.0h， 以91%的产率得到(2R,3R,4R,5S,6R)-2-((2S,3S,4S,5R,6R)-6-Fluoro-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-pyran-3-ylmethyl)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol
  参考文献：
  名称：

  Transfer reactions catalyzed by cyclodextrin glucosyltransferase using 4-thiomaltosyl and C-maltosyl fluorides as artificial donors

  摘要：

  Cyclodextrin glycosyltransferase enzyme from Bacillus circulans catalyzed the effective conversion of 4-thio-alpha-maltosyl fluoride into cyclo-alpha-(1-->4)-thiomalto -tetraoside, -pentaoside, -hexaoside and linear hemithiomaltooligosaccharides. However, under the same conditions, C-maltosyl fluoride afforded only linear modified maltotetraose, maltohexaose and maltooctaose in moderate yield. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0008-6215(97)00262-0