4-methoxyphenyl (α-D-galactofuranosyl)-(1->3)-(α-L-rhamnopyranosyl)-(1->2)-(α-L-rhamnopyranosyl)-(1->3)-(α-D-galactopyranosyl)-(1->3)-(β-D-galactopyranosyl)-(1->4)-β-D-glucopyranoside | 1203549-88-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-methoxyphenyl (α-D-galactofuranosyl)-(1->3)-(α-L-rhamnopyranosyl)-(1->2)-(α-L-rhamnopyranosyl)-(1->3)-(α-D-galactopyranosyl)-(1->3)-(β-D-galactopyranosyl)-(1->4)-β-D-glucopyranoside
• 英文别名: Galf(a1-3)Rha(a1-2)Rha(a1-3)Gal(a1-3)Gal(b1-4)Glc(b)-O-Ph(4-OMe)；(2S,3R,4R,5R,6S)-5-[(2S,3R,4R,5S,6S)-4-[(2R,3R,4R,5S)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy-3,5-dihydroxy-6-methyloxan-2-yl]oxy-6-[(2R,3R,4S,5S,6R)-2-[(2S,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-(4-methoxyphenoxy)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-methyloxane-3,4-diol
• CAS: 1203549-88-5
• 化学式: C₄₃H₆₈O₃₀
• 分子量: 1064.99
• InChiKey: HVTMPVUWXWVBMW-CDYKEWCLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -7.8
• 重原子数：
  73
• 可旋转键数：
  18
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  464
• 氢给体数：
  17
• 氢受体数：
  30

反应信息

• 作为产物：
  描述：

  在 20% palladium(II) hydroxide on carbon 、 氢气 作用下， 以 甲醇 为溶剂， 反应 24.0h， 以340 mg的产率得到4-methoxyphenyl (α-D-galactofuranosyl)-(1->3)-(α-L-rhamnopyranosyl)-(1->2)-(α-L-rhamnopyranosyl)-(1->3)-(α-D-galactopyranosyl)-(1->3)-(β-D-galactopyranosyl)-(1->4)-β-D-glucopyranoside
  参考文献：
  名称：

  Concise Synthesis of a Hexasaccharide Related to the Adhesin Receptor of Streptococcus oralis ATCC 55229

  摘要：

  A concise synthesis of a hexasaccharide related to the adhesin receptor of Streptococcus oralis ATCC 55229 (previously characterized as Streptococcus sanguis H1) has been achieved in excellent yield. A general glycosylation condition has been used throughout the synthetic scheme. All glycosylation steps and protecting group functionalization steps are high yielding and suitable for scale-up preparation.

  DOI：

  10.1080/07328300903261554