acetic acid 2-(2-methyl-6-oxocyclohex-1-enyl)-1-(2-oxo-2,5-dihydrofuran-3-yl)ethyl ester | 949562-89-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: acetic acid 2-(2-methyl-6-oxocyclohex-1-enyl)-1-(2-oxo-2,5-dihydrofuran-3-yl)ethyl ester
• 英文别名: [2-(2-methyl-6-oxocyclohexen-1-yl)-1-(5-oxo-2H-furan-4-yl)ethyl] acetate
• CAS: 949562-89-4
• 化学式: C₁₅H₁₈O₅
• 分子量: 278.305
• InChiKey: RXVIECVGKWIEBD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  69.7
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  acetic acid 2-(2-methyl-6-oxocyclohex-1-enyl)-1-(2-oxo-2,5-dihydrofuran-3-yl)ethyl ester 在 四乙基氯化铵 作用下， 以 水 、 乙腈 为溶剂， 反应 3.0h， 以59%的产率得到9a-methyl-1,5,5a,7,8,9,9a,9b-octahydronaphtho[1,2-c]furan-3,6-dione
  参考文献：
  名称：

  Electrohydrocyclization of alkoxy tether substituted mixed enone/enoate and bisenone systems: retention versus elimination

  摘要：

  The electrohydrocyclization of tethered enone/enoate or bisenone systems which contain an alkoxyl substituent in the tether was studied. Rather surprisingly, the cyclization of these compounds afforded very different products depending upon the alkoxy substituent. This behavior and its potential applications will be discussed. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2007.07.025
• 作为产物：
  描述：

  3-[1-hydroxy-2-(2-methyl-6-oxocyclohex-1-enyl)ethyl]-3-phenylsulfanyl-3,4-dihydrofuran-2-one 在 吡啶 、 4-二甲氨基吡啶 、 间氯过氧苯甲酸 作用下， 以 二氯甲烷 、 甲苯 为溶剂， 反应 3.0h， 生成 acetic acid 2-(2-methyl-6-oxocyclohex-1-enyl)-1-(2-oxo-2,5-dihydrofuran-3-yl)ethyl ester
  参考文献：
  名称：

  Electrohydrocyclization of alkoxy tether substituted mixed enone/enoate and bisenone systems: retention versus elimination

  摘要：

  The electrohydrocyclization of tethered enone/enoate or bisenone systems which contain an alkoxyl substituent in the tether was studied. Rather surprisingly, the cyclization of these compounds afforded very different products depending upon the alkoxy substituent. This behavior and its potential applications will be discussed. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2007.07.025

文献信息

• Electrohydrocyclization of alkoxy tether substituted mixed enone/enoate and bisenone systems: retention versus elimination
  作者：Renuka Manchanayakage、Duncan Omune、Christopher Hayes、Scott T. Handy

  DOI：10.1016/j.tet.2007.07.025

  日期：2007.9

  The electrohydrocyclization of tethered enone/enoate or bisenone systems which contain an alkoxyl substituent in the tether was studied. Rather surprisingly, the cyclization of these compounds afforded very different products depending upon the alkoxy substituent. This behavior and its potential applications will be discussed. (c) 2007 Elsevier Ltd. All rights reserved.