(E)-2-chloro-2-[(chloroimino)(phenyl)methyl]-1-phenylhexan-1-one | 1629803-30-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (E)-2-chloro-2-[(chloroimino)(phenyl)methyl]-1-phenylhexan-1-one
• CAS: 1629803-30-0
• 化学式: C₁₉H₁₉Cl₂NO
• 分子量: 348.272
• InChiKey: CWNJGUOLOVNWIK-OQKWZONESA-N

反应信息

• 作为反应物：
  描述：

  (E)-2-chloro-2-[(chloroimino)(phenyl)methyl]-1-phenylhexan-1-one 在 锌 作用下， 以 甲醇 为溶剂， 以70%的产率得到
  参考文献：
  名称：

  PhICl2-Mediated Conversion of Enamines into α,N-Dichloroimines and Their Reverse Conversion Mediated by Zinc in Methanol

  摘要：

  Treatment of enamine compounds with iodobenzene dichloride (PhICl2) conveniently gives a variety of alpha,N-dichloroimines in high yields. This approach allows the double insertion of the chloro moiety, which is postulated to take place via the iodobenzene dichloride mediated oxidative alpha-chlorination of the enamine substrates followed by further N-chlorination of the imine intermediates. Furthermore, the obtained alpha,N-dichloroimines could be converted reversely into the original enamines under reductive conditions using zinc in methanol.

  DOI：

  10.1055/s-0033-1341067
• 作为产物：
  描述：

  在 (二氯碘)-苯 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 0.5h， 以87%的产率得到(E)-2-chloro-2-[(chloroimino)(phenyl)methyl]-1-phenylhexan-1-one
  参考文献：
  名称：

  PhICl2-Mediated Conversion of Enamines into α,N-Dichloroimines and Their Reverse Conversion Mediated by Zinc in Methanol

  摘要：

  Treatment of enamine compounds with iodobenzene dichloride (PhICl2) conveniently gives a variety of alpha,N-dichloroimines in high yields. This approach allows the double insertion of the chloro moiety, which is postulated to take place via the iodobenzene dichloride mediated oxidative alpha-chlorination of the enamine substrates followed by further N-chlorination of the imine intermediates. Furthermore, the obtained alpha,N-dichloroimines could be converted reversely into the original enamines under reductive conditions using zinc in methanol.

  DOI：

  10.1055/s-0033-1341067