1L-N¹-benzyloxycarbonyl-O⁶-(2-benzyloxycarbonylamino-α-D-ribo-2,3-dideoxy-hexopyranosyl)-N³,O⁴-carbonyl-2-deoxy-streptamine | 73488-14-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1L-N¹-benzyloxycarbonyl-O⁶-(2-benzyloxycarbonylamino-α-D-ribo-2,3-dideoxy-hexopyranosyl)-N³,O⁴-carbonyl-2-deoxy-streptamine
• CAS: 73488-14-9
• 化学式: C₂₉H₃₅N₃O₁₁
• 分子量: 601.61
• InChiKey: IUXQOCOOVLLRLU-JRRXXZJNSA-N

反应信息

• 作为反应物：
  描述：

  1L-N¹-benzyloxycarbonyl-O⁶-(2-benzyloxycarbonylamino-α-D-ribo-2,3-dideoxy-hexopyranosyl)-N³,O⁴-carbonyl-2-deoxy-streptamine 、 2,2-二甲氧基丙烷 在 对甲苯磺酸 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 1L-N¹-benzyloxycarbonyl-O⁶-(2-benzyloxycarbonylamino-O⁴,O⁶-isopropylidene-α-D-ribo-2,3-dideoxy-hexopyranosyl)-N³,O⁴-carbonyl-2-deoxy-streptamine
  参考文献：
  名称：

  Syntheses of sporaricin analogues, 2-deoxy-4-N-glycyl-6-O-(.ALPHA.-nebrosaminyl)fortamine and its 3-de-O-methyl compound.

  摘要：

  2-Deoxy-4-N-glycyl-6-O-(α-nebrosaminyl)fortamine (21) and 3-de-O-methyl-2-deoxy-4-N-glycyl-6-O-(α-nebrosaminyl)fortamine (27) were prepared starting from lividamine. The syntheses include four key steps, that is, transformation of 2-deoxystreptamine moiety of lividamine to 4-N, 3-O-didemethyl-2-deoxyfortamine, selective 4-N-methylation of the new aminocyclitol moiety, selective attachment of a glycyl residue to the methylamino group at C-4 and selective amination at C-6'.

  DOI：

  10.7164/antibiotics.32.1137