methyl (α-L-rhamnopyranosyl)-(1->3)-[(α-D-glucopyranosyl)-(1->6)]-α-D-glucopyranoside | 1220097-74-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl (α-L-rhamnopyranosyl)-(1->3)-[(α-D-glucopyranosyl)-(1->6)]-α-D-glucopyranoside
• 英文别名: Rha(a1-3)[Glc(a1-6)]a-Glc1Me；(2S,3R,4R,5R,6S)-2-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-2-methoxy-6-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-4-yl]oxy-6-methyloxane-3,4,5-triol
• CAS: 1220097-74-4
• 化学式: C₁₉H₃₄O₁₅
• 分子量: 502.47
• InChiKey: IBEARFNBNWHHLZ-DMBOQMEWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.3
• 重原子数：
  34
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  237
• 氢给体数：
  9
• 氢受体数：
  15

反应信息

• 作为产物：
  描述：

  methyl (2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl)-(1->3)-[(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-(1->6)]-2-O-benzyl-α-D-glucopyranoside 在 10% Pd(OH)2 on carbon 、 氢气 作用下， 以 甲醇 为溶剂， 反应 24.0h， 以68%的产率得到methyl (α-L-rhamnopyranosyl)-(1->3)-[(α-D-glucopyranosyl)-(1->6)]-α-D-glucopyranoside
  参考文献：
  名称：

  Synthesis of Tri- and Disaccharide Fragments Related to the O-Antigen of Enteropathogenic Escherichia Coli O158

  摘要：

  Chemical synthesis of a tri- and a disaccharide related to the O-antigen of enteropathogenic E. coli O158 was achieved in high yield. In the disaccharide (2), one D-galactosamine unit is present in 1,2-cis-linked and the other is in the trans-orientation, and both of them were prepared from the same intermediate by tuning the reaction solvent. Yields were considerably high in all steps.

  DOI：

  10.1080/07328300903477804

文献信息

• Synthesis of Tri- and Disaccharide Fragments Related to the <i>O</i>-Antigen of Enteropathogenic <i>Escherichia Coli</i> O158
  作者：Rajib Panchadhayee、Anup Kumar Misra

  DOI：10.1080/07328300903477804

  日期：2010.1.14

  Chemical synthesis of a tri- and a disaccharide related to the O-antigen of enteropathogenic E. coli O158 was achieved in high yield. In the disaccharide (2), one D-galactosamine unit is present in 1,2-cis-linked and the other is in the trans-orientation, and both of them were prepared from the same intermediate by tuning the reaction solvent. Yields were considerably high in all steps.