2-[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-(Hydroxymethyl)-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]-1-phenylethanone | 427901-28-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-(Hydroxymethyl)-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]-1-phenylethanone
• 英文别名: 2-[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-(hydroxymethyl)-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]-1-phenylethanone
• CAS: 427901-28-8
• 化学式: C₁₂₀H₁₀₄O₁₈
• 分子量: 1834.13
• InChiKey: JCDDLNSGWUOINT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  24.4
• 重原子数：
  138
• 可旋转键数：
  50
• 环数：
  17.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  185
• 氢给体数：
  1
• 氢受体数：
  18

反应信息

• 作为反应物：
  描述：

  2-[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-(Hydroxymethyl)-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]-1-phenylethanone 在 三苯基膦 作用下， 以 四氢呋喃 为溶剂， 反应 0.08h， 以96%的产率得到
  参考文献：
  名称：

  The Effect of Macromolecular Architecture in Nanomaterials:  A Comparison of Site Isolation in Porphyrin Core Dendrimers and Their Isomeric Linear Analogues

  摘要：

  The influence of macromolecular architecture on the physical properties of polymeric materials has been studied by comparing poly(benzyl ether) dendrons with their exact linear analogues. The results clearly confirm the anticipation that dendrimers are unique when compared to other architectures. Physical properties, from hydrodynamic volume to crystallinity, were shown to be different, and in a comparative study of core encapsulation in macromolecules of different architecture, energy transduction from the polymer backbone to a porphyrin core was shown to be different for dendrimers as compared to that of isomeric four- or eight-arm star polymers. Fluorescence excitation revealed strong, morphology dependent intramolecular energy transfer in the three macromolecular isomers investigated, Even at high generations, the dendrimers exhibited the most efficient energy transfer, thereby indicating that the dendritic architecture affords superior site isolation to the central porphyrin it surrounds.

  DOI：

  10.1021/ja025536u
• 作为产物：
  描述：

  3-Benzyloxy-5-{3-benzyloxy-5-[3-benzyloxy-5-(3-benzyloxy-5-hydroxymethyl-phenoxymethyl)-phenoxymethyl]-phenoxymethyl}-phenol 、 2-(3-Benzyloxy-5-{3-benzyloxy-5-[3-benzyloxy-5-(3-benzyloxy-5-bromomethyl-phenoxymethyl)-phenoxymethyl]-phenoxymethyl}-phenoxy)-1-phenyl-ethanone 在 18-冠醚-6 、 potassium carbonate 作用下， 以 丙酮 为溶剂， 反应 16.0h， 以96%的产率得到2-[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-(Hydroxymethyl)-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]methyl]-5-phenylmethoxyphenoxy]-1-phenylethanone
  参考文献：
  名称：

  The Effect of Macromolecular Architecture in Nanomaterials:  A Comparison of Site Isolation in Porphyrin Core Dendrimers and Their Isomeric Linear Analogues

  摘要：

  The influence of macromolecular architecture on the physical properties of polymeric materials has been studied by comparing poly(benzyl ether) dendrons with their exact linear analogues. The results clearly confirm the anticipation that dendrimers are unique when compared to other architectures. Physical properties, from hydrodynamic volume to crystallinity, were shown to be different, and in a comparative study of core encapsulation in macromolecules of different architecture, energy transduction from the polymer backbone to a porphyrin core was shown to be different for dendrimers as compared to that of isomeric four- or eight-arm star polymers. Fluorescence excitation revealed strong, morphology dependent intramolecular energy transfer in the three macromolecular isomers investigated, Even at high generations, the dendrimers exhibited the most efficient energy transfer, thereby indicating that the dendritic architecture affords superior site isolation to the central porphyrin it surrounds.

  DOI：

  10.1021/ja025536u

文献信息

• The Effect of Macromolecular Architecture in Nanomaterials:  A Comparison of Site Isolation in Porphyrin Core Dendrimers and Their Isomeric Linear Analogues
  作者：Eva M. Harth、Stefan Hecht、Brett Helms、Eva E. Malmstrom、Jean M. J. Fréchet、Craig J. Hawker

  DOI：10.1021/ja025536u

  日期：2002.4.1

  The influence of macromolecular architecture on the physical properties of polymeric materials has been studied by comparing poly(benzyl ether) dendrons with their exact linear analogues. The results clearly confirm the anticipation that dendrimers are unique when compared to other architectures. Physical properties, from hydrodynamic volume to crystallinity, were shown to be different, and in a comparative study of core encapsulation in macromolecules of different architecture, energy transduction from the polymer backbone to a porphyrin core was shown to be different for dendrimers as compared to that of isomeric four- or eight-arm star polymers. Fluorescence excitation revealed strong, morphology dependent intramolecular energy transfer in the three macromolecular isomers investigated, Even at high generations, the dendrimers exhibited the most efficient energy transfer, thereby indicating that the dendritic architecture affords superior site isolation to the central porphyrin it surrounds.