trans-cinnamic acid-(2-methoxy-4-propyl-phenyl ester) | 1876-09-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: trans-cinnamic acid-(2-methoxy-4-propyl-phenyl ester)
• 英文别名: trans-Zimtsaeure-(2-methoxy-4-propyl-phenylester)
• CAS: 1876-09-1
• 化学式: C₁₉H₂₀O₃
• 分子量: 296.366
• InChiKey: RAKKCELBWFUPDY-ACCUITESSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.27
• 重原子数：
  22.0
• 可旋转键数：
  6.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  35.53
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  二氢丁香酚 、 3-苯基-2-丙烯酰氯 在 吡啶 、 氯仿 作用下， 生成 trans-cinnamic acid-(2-methoxy-4-propyl-phenyl ester)
  参考文献：
  名称：

  Gauthier, Annales de Chimie (Cachan, France), 1945, vol. <11> 20, p. 581,608

  摘要：

  DOI：

文献信息

• Compositions for treatment of dermatological diseases and conditions and methods of use thereof
  申请人：DermaMedics, LLC

  公开号：US10869822B2

  公开（公告）日：2020-12-22

  Compositions containing an effective dermatological disease-treating or dermatological condition-treating active agent and a pharmaceutically-acceptable carrier or vehicle are disclosed. Methods of using the compositions are also disclosed.

  本发明公开了含有有效的皮肤病治疗或皮肤状况治疗活性剂和药学上可接受的载体或载体的组合物。还公开了使用这些组合物的方法。
• METHODS AND COMPOSITIONS FOR TREATING DERMATOLOGICAL DISEASES AND CONDITIONS
  申请人：Therametics, Llc

  公开号：EP2244690A1

  公开（公告）日：2010-11-03
• COMPOSITIONS FOR USE IN TREATMENT OF DERMATOLOGICAL DISEASES AND CONDITIONS
  申请人：DermaMedics, LLC

  公开号：US20130274231A1

  公开（公告）日：2013-10-17

  Compositions containing an effective dermatological disease-treating or dermatological condition-treating active agent and a pharmaceutically-acceptable carrier or vehicle are disclosed.
• COMPOSITIONS FOR TREATING HYPERPIGMENTATION AND METHODS OF USE THEREOF
  申请人：DermaMedics, LLC

  公开号：US20130289006A1

  公开（公告）日：2013-10-31

  Compositions are disclosed that contain an effective hyperpigmentation-treating active agent and a pharmaceutically-acceptable carrier or vehicle. Methods of using the compositions to treat hyperpigmentation are also disclosed.
• COMPOSITIONS FOR USE IN TREATMENT OF DERMATOLOGICAL DISEASES AND CONDITIONS AND METHODS OF USE THEREOF
  申请人：DermaMedics, LLC

  公开号：US20130280195A1

  公开（公告）日：2013-10-24

  Compositions containing an effective dermatological disease-treating or dermatological condition-treating active agent and a pharmaceutically-acceptable carrier or vehicle are disclosed. Methods of using the compositions are also disclosed.