(E)-1-cyclopentyl-3-phenylprop-2-en-1-one | 119729-81-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (E)-1-cyclopentyl-3-phenylprop-2-en-1-one
• 英文别名: 3-phenyl-2-propenoylcyclopentane；1-cyclopentyl-3t-phenyl-propenone；1-Cyclopentyl-3t-phenyl-propenon
• CAS: 119729-81-6
• 化学式: C₁₄H₁₆O
• 分子量: 200.28
• InChiKey: YADUFVLFHODGSH-ZHACJKMWSA-N

物化性质

• 沸点：
  339.4±11.0 °C(Predicted)
• 密度：
  1.060±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (E)-1-cyclopentyl-3-phenylprop-2-en-1-one 在 溴 作用下， 生成 2,3-dibromo-1-cyclopentyl-3-phenyl-propan-1-one
  参考文献：
  名称：

  Ultraviolet Absorption Spectra of Alicyclic Compounds. III. Phenyl Cycloalkyl and Styryl Cycloalkyl Ketones¹

  摘要：

  DOI：

  10.1021/ja01122a070
• 作为产物：
  描述：

  环戊酸 在 sodium hydroxide 、 manganese(II)carbonate 作用下， 生成 (E)-1-cyclopentyl-3-phenylprop-2-en-1-one
  参考文献：
  名称：

  Ultraviolet Absorption Spectra of Alicyclic Compounds. III. Phenyl Cycloalkyl and Styryl Cycloalkyl Ketones¹

  摘要：

  DOI：

  10.1021/ja01122a070

文献信息

• Acylcobalt salophen reagents. Precursors to acyl radical intermediates for inter- and intra-molecular oxidative michael addition reactions
  作者：Donal J. Coveney、Vinod F. Patel、Gerald Pattenden

  DOI：10.1016/s0040-4039(01)81098-4

  日期：1987.1

  Acylcobalt salophens (2) undergo homolytic cleavage (Δ, sunlamp) producing acyl radicals (10) which undergo oxidative additions to activated carbon-to-carbon double bonds leading to enones and functionalised ring systems e.g. (3)→(4); (5)→(6); (7)→(8); (12)→(13); and (14)→(15).

  酰基钴盐分子（2）经历均相裂解（Δ，日光），产生酰基基团（10），这些基团经过氧化加成到活性碳-碳双键上，形成烯酮和官能化的环系，例如（3）→（4）；（5）→（6）；（7）→（8）；（12）→（13）; （14）→（15）。
• Synergistic chalcone containing composition of a nematicide
  申请人：TELLURIS BIOTECH INDIA PRIVATE LIMITED

  公开号：US10925286B2

  公开（公告）日：2021-02-23

  The present invention provides a synergistic composition of a nematicide comprising of a nematicidal peptide, and chalcones, wherein the nematicidal peptide is derived from CED-4 protein sequence is either, Peptide 2, or Peptide 3, or Peptide 12; and chalcones are either chalcone 17, chalcone 25, or chalcone 30. The nematicidal peptides alone show 100% nematicidal activity at a concentration of 1 mg/ml, whereas, when combined with chalcones, 100% nematicidal activity is seen at concentration as low as 0.8 mg/ml bringing a synergistic effect. Another embodiment of the invention provides a method for preparing working solutions of chalcones in aqueous solvents such as water by diluting the stock solution of chalcones, prepared in dimethyl sulfoxide, serially in ethanol and water. The final concentration of chalcone is around 10−4-10−5 M in the nematicidal composition. This synergistic nematicidal composition is environmentally safe and non-toxic to humans and animals.

  本发明提供了一种由杀线虫肽和查尔酮组成的杀线虫剂协同组合物，其中杀线虫肽来源于 CED-4 蛋白序列，即肽 2、肽 3 或肽 12；查尔酮为查尔酮 17、查尔酮 25 或查尔酮 30。单独的杀线虫肽在浓度为 1 毫克/毫升时显示出 100%的杀线虫活性，而当与查尔酮结合使用时，在低至 0.8 毫克/毫升的浓度下就能显示出 100%的杀线虫活性，从而产生协同效应。本发明的另一个实施方案提供了一种在水性溶剂（如水中）中制备查耳酮工作溶液的方法，该方法是将在二甲亚砜中制备的查耳酮储备溶液在乙醇和水中依次稀释。杀线虫成分中查尔酮的最终浓度约为 10-4-10-5 M。这种协同杀线虫组合物对环境安全，对人类和动物无毒。
• Synergistic composition of nematicide comprising of chalcones
  申请人：TELLURIS BIOTECH INDIA PRIVATE LIMITED

  公开号：US11369111B2

  公开（公告）日：2022-06-28

  The present invention provides a synergistic composition of a nematicide comprising of combination of chalcones, chalcone 17 and chalcone 25, or chalcone 17 and chalcone 30 with potent nematicidal and nematostatic properties. The chalcones individually show 100% nematicidal activity at a concentration as high as 10−2-10−3 M, whereas, the combination of chalcone 17 and chalcone 25, or chalcone 17 and chalcone 30, show 100% nematicidal activity at concentration as low as 10−4-10−6 M bringing a synergistic effect, wherein the ratio of the chalcones is 1:1. These combinations of the chalcones also show potent nematostatic activity compared to each chalcone individually. This synergistic nematicidal composition is environmentally safe and non-toxic to humans and animals.

  本发明提供了一种杀线虫剂的增效组合物，该组合物由查尔酮、查尔酮 17 和查尔酮 25 或查尔酮 17 和查尔酮 30 组合而成，具有强大的杀线虫和线虫抑制特性。单独的查耳酮在浓度高达 10-2-10-3 M 时显示出 100% 的杀线虫活性，而查耳酮 17 和查耳酮 25 或查耳酮 17 和查耳酮 30 的组合在浓度低至 10-4-10-6 M 时显示出 100% 的杀线虫活性，从而产生协同效应，其中查耳酮的比例为 1:1。与单独使用每种查尔酮相比，这些查尔酮组合也显示出强大的杀线虫活性。这种协同杀线虫成分对环境安全，对人类和动物无毒。
• Jacquier et al., Bulletin de la Societe Chimique de France, 1956, p. 1653,1664
  作者：Jacquier et al.

  DOI：——

  日期：——
• Coveney, Donal J.; Patel, Vinod F.; Pattenden, Gerald, Journal of the Chemical Society. Perkin transactions I, 1990, # 10, p. 2721 - 2729
  作者：Coveney, Donal J.、Patel, Vinod F.、Pattenden, Gerald、Thompson, David M.

  DOI：——

  日期：——