(1,2-ethylenediamine)(1,1-cyclobutanedicaboxylato)palladium(II) monohydrate | 214846-19-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (1,2-ethylenediamine)(1,1-cyclobutanedicaboxylato)palladium(II) monohydrate
• 英文别名: cyclobutane-1,1-dicarboxylate;ethane-1,2-diamine;palladium(2+)
• CAS: 214846-19-2
• 化学式: C₈H₁₄N₂O₄Pd
• 分子量: 308.63
• InChiKey: BHUATDYQGQIAOD-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  (1,2-ethylenediamine)(1,1-cyclobutanedicaboxylato)palladium(II) monohydrate 以 neat (no solvent) 为溶剂， 生成 palladium(II) oxide
  参考文献：
  名称：

  Synthesis, characterization, solution equilibria and DNA binding of some mixed-ligand palladium(II) complexes. Thermodynamic models for carboplatin drug and analogous compounds

  摘要：

  A series of ternary complexes of palladium(II) with ethylenediamine (en) and dicarboxylate ligands of the type [Pd(en)L], where L = malonato (I), methylinalonato (II), dimethylmalonato (III) and 1,1-cyclobutanedicarboxylato (IV), were synthesized and characterized by elemental analysis, IR spectroscopy and TG-DTA thermal analysis. The X-ray crystal structures for the compounds H and IV are described. The stability of these dicarboxylato complexes in aqueous solution has been investigated by potentiometric measurements. The formation constants calculated for these dicarboxylato complexes and those reported in the literature for the corresponding hydroxo- and chloro- complexes of the Pd(en) moiety have been used to obtain species distribution diagrams. In addition, the interaction of the dicarboxylato complexes and the dichloro complex [Pd(en)Cl-2] (V) with DNA was studied by various methods. UV spectral data and melting curves do not reveal differences in the reactivity of these complexes with DNA. This and other features are correlated with the stability of the complexes studied. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0020-1693(02)01071-x
• 作为产物：
  描述：

  乙二胺氯化钯(II) 、 1,1-环丁基二甲酸 在 sodium hydroxide 、 silver nitrate 作用下， 以 水 为溶剂， 以80%的产率得到(1,2-ethylenediamine)(1,1-cyclobutanedicaboxylato)palladium(II) monohydrate
  参考文献：
  名称：

  Kinetics and mechanisms of the ligand substitution reactions of bis(amine)(cyclobutane-1,1-dicarboxylato)palladium(II) †

  摘要：

  关于双齿环丁烷-1,1-二羧酸配体（cbdca）从复合物 [Pd(en)(cbdca)]（en = 乙二胺）和 [Pd(bpy)(cbdca)]（bpy = 2,2'-联吡啶）中位移的动力学和机理研究已经完成。观察到在用硫脲（tu）、四甲基硫脲（tmtu）、肌苷5'-单磷酸（5'-IMP）和碘离子以及酸催化水解反应替代cbdca的过程中，有两个连续的反应步骤。在tu和tmtu取代cbdca后，Pd-结合的含硫亲核试剂的强反向效应导致en配体从 [Pd(en)(cbdca)] 中位移，而对此复合物 [Pd(bpy)(cbdca)] 并未观察到类似的反应。所有的速率和活化参数与联系取代机理相一致。

  DOI：

  10.1039/a804141e