2-benzyl-4,5-dichlorocyclopent-4-ene-1,3-dione | 1115190-65-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-benzyl-4,5-dichlorocyclopent-4-ene-1,3-dione
• 英文别名: 2-Benzyl-4,5-dichlorocyclopent-4-ene-1,3-dione
• CAS: 1115190-65-2
• 化学式: C₁₂H₈Cl₂O₂
• 分子量: 255.1
• InChiKey: WGFDZVRVADAHAH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-benzyl-2,4,5-trichlorocyclopent-4-ene-1,3-dione 在 chromium dichloride 、 盐酸 作用下， 以 水 、 丙酮 为溶剂， 以40%的产率得到2-benzyl-4,5-dichlorocyclopent-4-ene-1,3-dione
  参考文献：
  名称：

  Some reactions of 5-benzyl-2,3,5-trichloro-4,4-dimethoxy-cyclopent-2-en-1-one and its derivatives

  摘要：

  5-Benzyl-2,3,5-trichloro-4.4-dimethoxycyclopent-2-en-1-one and 2-benzyl-2,4,5-trichlorocyclopent-4-ene-1,3-dione were Subjected to dehydrochlorination by the action of 1,4-diazabicyclo[2.2.2] octane, selective dechlorination at C-5 by the action of CrCl2, and Ad(N)E replacement of the chlorine atom at C-3 by the action of secondary amines. The reduction of 2-benzyl-2,4-dichloro-5-morpholinocyclopent-4-ene-1,3-dione with sodium tetrahydridoborate in methanol and ethanol gave different products.

  DOI：

  10.1134/s107042800804009x

文献信息

• Some reactions of 5-benzyl-2,3,5-trichloro-4,4-dimethoxy-cyclopent-2-en-1-one and its derivatives
  作者：F. A. Gimalova、V. A. Egorov、M. S. Miftakhov

  DOI：10.1134/s107042800804009x

  日期：2008.4

  5-Benzyl-2,3,5-trichloro-4.4-dimethoxycyclopent-2-en-1-one and 2-benzyl-2,4,5-trichlorocyclopent-4-ene-1,3-dione were Subjected to dehydrochlorination by the action of 1,4-diazabicyclo[2.2.2] octane, selective dechlorination at C-5 by the action of CrCl2, and Ad(N)E replacement of the chlorine atom at C-3 by the action of secondary amines. The reduction of 2-benzyl-2,4-dichloro-5-morpholinocyclopent-4-ene-1,3-dione with sodium tetrahydridoborate in methanol and ethanol gave different products.