N,N-bis<2-(methoxymethoxy)-2-propenyl>-4-aminobutanal diethylacetal | 158629-48-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N,N-bis<2-(methoxymethoxy)-2-propenyl>-4-aminobutanal diethylacetal
• CAS: 158629-48-2
• 化学式: C₁₈H₃₅NO₆
• 分子量: 361.479
• InChiKey: SDFFHQFGBHODHY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.74
• 重原子数：
  25.0
• 可旋转键数：
  18.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  58.62
• 氢给体数：
  0.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  N,N-bis<2-(methoxymethoxy)-2-propenyl>-4-aminobutanal diethylacetal 在 草酸 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 以92%的产率得到N,N-bis<2-(methoxymethoxy)-2-propenyl>-4-aminobutanal
  参考文献：
  名称：

  On the Hodge mechanism of the formation of the bread flavor component 6-acetyl-1,2,3,4-tetrahydropyridine from proline and sugars

  摘要：

  The so-called Hodge mechanism for the generation of 6-acetyl-1,2,3,4-tetrahydropyridine, a major Maillard flavor compound in processed foods, from proline and 1,2-propanedione most probably does not involve the intermediacy of N-acetonyl-4-aminobutanal. This finding is based on model experiments in which suitably and doubly protected N-acetonyl-4-aminobutanal was hydrolyzed into the parent compound and in which no trace of the flavor compound could be detected.

  DOI：

  10.1021/jf00044a031
• 作为产物：
  描述：

  1-氯-2-(氯甲基)-3,5-二氧杂己烷 在 四丁基硫酸氢铵 、 potassium carbonate 作用下， 以 二氯甲烷 为溶剂， 反应 15.0h， 生成 N,N-bis<2-(methoxymethoxy)-2-propenyl>-4-aminobutanal diethylacetal
  参考文献：
  名称：

  On the Hodge mechanism of the formation of the bread flavor component 6-acetyl-1,2,3,4-tetrahydropyridine from proline and sugars

  摘要：

  The so-called Hodge mechanism for the generation of 6-acetyl-1,2,3,4-tetrahydropyridine, a major Maillard flavor compound in processed foods, from proline and 1,2-propanedione most probably does not involve the intermediacy of N-acetonyl-4-aminobutanal. This finding is based on model experiments in which suitably and doubly protected N-acetonyl-4-aminobutanal was hydrolyzed into the parent compound and in which no trace of the flavor compound could be detected.

  DOI：

  10.1021/jf00044a031