methyl 3-C-(hydroxymethyl)-β-D-erythrofuranoside | 64481-65-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl 3-C-(hydroxymethyl)-β-D-erythrofuranoside
• 英文别名: β-D-1-O-methylapiofuranose；methyl β-D-apiofuranoside；methyl β-D-apiose；3-C-(hydroxymethyl)-β-D-erythro-tetrafuranoside；(2R,3R,4R)-4-(hydroxymethyl)-2-methoxyoxolane-3,4-diol
• CAS: 64481-65-8
• 化学式: C₆H₁₂O₅
• 分子量: 164.158
• InChiKey: MMMUONSALCOBMP-KVQBGUIXSA-N

物化性质

• 沸点：
  339.6±42.0 °C(Predicted)
• 密度：
  1.40±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  79.2
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  methyl 3-C-(hydroxymethyl)-β-D-erythrofuranoside 在 硼酸 作用下， 以 重水 为溶剂， 以5%的产率得到
  参考文献：
  名称：

  NMR spectroscopic analysis of the borate diol esters of methyl apiofuranosides

  摘要：

  The borate diol esters formed by reacting methyl beta-D- and methyl beta-L-apiofuranosides with boric acid were studied by B-11, H-1 and C-13 NMR spectroscopy, and by FABMS. Methyl beta-D-apiofuranoside was shown to form more stable borate diol diesters and a monoester than those of methyl beta-L-apiofuranoside. The borate diol diesters of methyl beta-D-apiofuranoside are present as two diastereomers in approximately equal molar ratios. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(99)00184-6
• 作为产物：
  描述：

  (2R,3R,4R,5S,6R)-2-[[(3R,4R,5S)-3,4-dihydroxy-5-[(1R,2S,4S,5'R,6R,7S,8S,9S,10S,12S,13R,16S)-5',7,9,13-tetramethyl-10-[(2R,3R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxyoxolan-3-yl]methoxy]-6-methyloxane-3,4,5-triol 生成 methyl 3-C-(hydroxymethyl)-β-D-erythrofuranoside
  参考文献：
  名称：

  NAKANO, KIMIKO;MURAKAMI, KOTARO;TAKAISHI, YOSHIHISA;TOMIMATSU, TOSHIAKI;N+, CHEM. AND PHARM. BULL., 37,(1989) N, C. 116-118

  摘要：

  DOI：

文献信息

• Synthesis, separation and NMR spectral analysis of methyl apiofuranosides
  作者：Tadashi Ishii、Masayuki Yanagisawa

  DOI：10.1016/s0008-6215(98)00262-6

  日期：1998.12

  Abstract Methyl apiofuranosides were prepared by methanolysis of d -apiose. Four methyl apiofuranosides were separated by ion-exclusion and normal phase chromatography and their structures were characterized by 1 H and 13 C NMR spectroscopy. The composition of methyl apiofuranosides was almost the same as that of d -apiose in D 2 O.

  摘要通过d-apiose的甲醇水解反应制备了甲基apiofuranosides。通过离子排斥法和正相色谱法分离出四种甲基呋喃呋喃糖苷，并通过1 H和13 C NMR光谱对它们的结构进行了表征。甲基apiofuranosides的组成与D 2 O中的d -apiose几乎相同。
• Structure of desacylsaponins obtained from the bark of Quillaja saponaria
  作者：Ryuichi Higuchi、Yoshinori Tokimitsu、Toshihiro Fujioka、Tetsuya Komori、Toshio Kawasaki、David G. Oakenful

  DOI：10.1016/s0031-9422(00)81518-6

  日期：1986.12
• AQUINO, RITA;DAGOSTINO, MARIO;DE, SIMONE FRANCESCO;PIZZA, COSIMO, PHYTOCHEMISTRY, 27,(1988) N 6, C. 1827-1830
  作者：AQUINO, RITA、DAGOSTINO, MARIO、DE, SIMONE FRANCESCO、PIZZA, COSIMO

  DOI：——

  日期：——