| 220325-91-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• CAS: 220325-91-7
• 化学式: C₂₆H₃₈O₈
• 分子量: 478.583
• InChiKey: JEPXCMFVVFEXIG-CVXPQZAVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.13
• 重原子数：
  34.0
• 可旋转键数：
  7.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  108.36
• 氢给体数：
  1.0
• 氢受体数：
  8.0

反应信息

• 作为反应物：
  描述：

  在 Dowex W₅₀x2 (H⁽¹⁺⁾) resin 、 三苯基膦 、 偶氮二甲酸二乙酯 作用下， 以 四氢呋喃 、 甲醇 、 水 为溶剂， 反应 1.33h， 生成
  参考文献：
  名称：

  Effects of 17-alkyl-16,17-dihydrogibberellin A5 derivatives on growth and flowering in Lolium temulentum

  摘要：

  Several gibberellins in which the 16-methyl group of the 16-epimers of dihydro-GA(5) had been replaced by ethyl, n-propyl and n-butyl were prepared and tested at doses of 1, 5 or 25&mgr;g per plant for their effects on stem growth and flowering of the grass Lolium temulentum. The ethyl and n-propyl derivatives were most inhibitory of elongation, the exo-isomers being more active than the endo-forms. While both isomers of dihydro-GA(5) promoted flowering, among the 17-alkyl analogues, only the exo-ethyl derivative showed significant activity.

  DOI：

  10.1016/s0031-9422(98)00285-4
• 作为产物：
  描述：

  (1S,2S,4aR,4bR,7S,9aS,10S,10aR)-8-(but-1-en-1-yl)-10-((methoxymethoxy)carbonyl)-1-methyl-13-oxo-1,2,5,6,8,9,10,10a-octahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-2,7(4bH)-diyl diacetate 在 rhodium on alumina 氢气 、 potassium carbonate 作用下， 以 甲醇 、 乙酸乙酯 为溶剂， 反应 17.5h， 生成
  参考文献：
  名称：

  Effects of 17-alkyl-16,17-dihydrogibberellin A5 derivatives on growth and flowering in Lolium temulentum

  摘要：

  Several gibberellins in which the 16-methyl group of the 16-epimers of dihydro-GA(5) had been replaced by ethyl, n-propyl and n-butyl were prepared and tested at doses of 1, 5 or 25&mgr;g per plant for their effects on stem growth and flowering of the grass Lolium temulentum. The ethyl and n-propyl derivatives were most inhibitory of elongation, the exo-isomers being more active than the endo-forms. While both isomers of dihydro-GA(5) promoted flowering, among the 17-alkyl analogues, only the exo-ethyl derivative showed significant activity.

  DOI：

  10.1016/s0031-9422(98)00285-4