2-Aminoacetic acid;(3-carboxy-2-propanoyloxypropyl)-trimethylazanium;chloride | 423152-20-9

• 物质功能分类: 生物化工 - 氨基酸及其衍生物 - 甘氨酸类衍生物
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-Aminoacetic acid;(3-carboxy-2-propanoyloxypropyl)-trimethylazanium;chloride
• 英文别名: 2-aminoacetic acid;(3-carboxy-2-propanoyloxypropyl)-trimethylazanium;chloride
• CAS: 423152-20-9
• 化学式: C12H25ClN2O6
• 分子量: 328.79
• InChiKey: KNYIDCDOKIOINV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.39
• 重原子数：
  21
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  130
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• GEL USEFUL FOR THE DELIVERY OF COSMETIC ACTIVE INGREDIENTS
  申请人：SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A.

  公开号：EP2152225A1

  公开（公告）日：2010-02-17
• THICKENED AMINO ACID SURFACTANT COMPOSITIONS AND METHODS THEREFOR
  申请人：Lubrizol Advanced Materials, Inc.

  公开号：EP2558525B2

  公开（公告）日：2018-04-04
• EQUINE NUTRITIONAL SUPPLEMENT
  申请人：Equine Nutriceuticals, LLC

  公开号：EP2665473A2

  公开（公告）日：2013-11-27
• JP2011001375A
  申请人：——

  公开号：JP2011001375A

  公开（公告）日：2011-01-06
• Compositions and methods for lowering plasma concentrations of low density lipoproteins in humans
  申请人：Smith L. Michael

  公开号：US20070072910A1

  公开（公告）日：2007-03-29

  The present invention is directed to compositions and method to lower the plasma concentration of a low density lipoprotein in a human. One aspect is the invention is directed to compositions comprising at least one pharmaceutically acceptable L-carnitine compound and at least one pharmaceutically acceptable niacin compound, in such amount as to reduce the concentration of a low density lipoprotein. Another embodiment is directed to a composition of L-carnitine and niacin that substantially reduces side-effects associated with niacin treatment. Another aspect of the invention relates to a method for treating hyperlipidemia while substantially reducing side-effects associated with niacin treatment by administering a composition of L-carnitine and niacin.